ArticleBMC surgery2026
Concurrent lumbar degenerative disease is independently associated with chronic post-surgical pain after total knee arthroplasty for knee osteoarthritis: a retrospective study.
Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveChronic post-surgical pain (CPSP) after total knee arthroplasty (TKA) remains a significant clinical challenge. This study aimed to investigate the association between concurrent lumbar degenerative disease (LDD) and CPSP after TKA for knee osteoarthritis (KOA).
methodsA total of 348 KOA patients undergoing first unilateral TKA (June 2023-June 2025) were enrolled and stratified into LDD (n = 167) and non-LDD (n = 181) groups. CPSP incidence, pain severity, and postoperative knee function were compared. Logistic regression models were constructed to identify influencing factors for CPSP after TKA.
resultsAt 6 months postoperatively, both groups showed significant improvements in knee function, mobility, and pain (all P < 0.05). Compared with the non-LDD group, the LDD group exhibited lower knee society scores, reduced knee range of motion, a shorter 6-minute walk distance, a longer timed up and go test time, higher visual analogue scale (VAS) scores for pain at rest and during activity, a higher rate of non-steroidal anti-inflammatory drug use, and a higher incidence of CPSP (all P < 0.05). Depression/anxiety history, preoperative VAS scores, and LDD were independently associated with CPSP after TKA in patients with KOA (all P < 0.05). Among patients with KOA with concurrent LDD, depression/anxiety history, preoperative VAS scores, and preoperative radicular symptoms were independently associated with CPSP after TKA (all P < 0.05).
conclusionLDD is independently associated with CPSP after TKA. In patients with KOA with concurrent LDD, preoperative radicular symptoms, depression/anxiety history, and intense preoperative pain further increase CPSP risk.
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