Evidence map›Paper›PMID 42157016›Full record

ReviewNature reviews. Gastroenterology & hepatology2026

Precision nutrition for the prevention and management of inflammatory bowel disease.

Jie Chen, Lintao Dan, Judith Wellens, Vipul Jairath, Henit Yanai, Hamed Khalili, Silvio Danese, Laurent Peyrin-Biroulet, Xiaoyan Wang, Xue Li and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jie Chen *Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID http://orcid.org/0000-0002-4029-4192
Lintao Dan *Department of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID http://orcid.org/0000-0001-5963-2772
Judith WellensDepartment of Gastroenterology and Hepatology, Leuven University Hospital, Leuven, Belgium.ORCID http://orcid.org/0000-0002-1647-8151
Vipul JairathDepartment of Medicine, Western University, London, Ontario, Canada.
Henit YanaiIBD Center, Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel.ORCID http://orcid.org/0000-0001-5483-5271
Hamed KhaliliDivision of Gastroenterology, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7956-6941
Silvio DaneseDepartment of Gastroenterology and Endoscopy, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.ORCID http://orcid.org/0000-0001-7341-1351
Laurent Peyrin-BirouletDepartment of Gastroenterology and Inserm NGERE U1256, University Hospital of Nancy, University of Lorraine, Vandoeuvre-les-Nancy, France.ORCID http://orcid.org/0000-0003-2536-6618
Xiaoyan WangDepartment of Gastroenterology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China. wangxiaoyan@csu.edu.cn.
Xue LiDepartment of Big Data in Health Science, School of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. xueli157@zju.edu.cn.ORCID http://orcid.org/0000-0001-6880-2577
Fernando MagroCINTESIS@RISE Department, Faculdade de Medicina da Universidade do Porto, Porto, Portugal. fm@med.up.pt.ORCID http://orcid.org/0000-0003-2634-9668

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rising disease burden of inflammatory bowel disease (IBD) parallels the changing dietary landscape accompanying industrialization, underscoring the growing relevance of nutritional science in disease prevention and management. Precision nutrition has emerged as a promising approach to prevent and manage IBD through tailored dietary recommendations based on multidimensional individual characteristics, including demographics, disease natural history and multiomics traits. In this Review, we investigate the sources of heterogeneity in dietary responses and propose a stepwise framework for precision nutrition: phenotype-based precision nutrition, informed by general phenotypes in clinical and community settings; omics-based precision nutrition, targeting subgroups with shared biological features identified via omics and complementary approaches; and integrated precision nutrition, providing personalized dietary strategies informed by comprehensive, multidimensional phenotypes. Advances in large-scale longitudinal multiomics cohorts, biomarker detection and artificial intelligence are transforming data acquisition and interpretation, thereby facilitating both interventional research and real-world application of precision nutrition. Key considerations for implementing precision nutrition in IBD are discussed. This Review outlines a holistic and translational framework, aiming to advance both research and clinical practice in the prevention and management of IBD.

Indexed as

Inflammatory Bowel DiseasesPrecision MedicineDietHumansMultiomicsPhenotype

Identifiers

PMID42157016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.