Evidence map›Paper›PMID 42156830›Full record

Trial reportScientific reports2026

Impact of stem cell therapy on brain metabolic profile in cerebral palsy assessed by magnetic resonance spectroscopy in a randomized clinical trial.

Melika Jameie, Neda Pak, Mehrdad Mozafar, Hadis Farazmand, Elaheh Khodadoust, Anahita Majmaa, Mobina Amanollahi, Morteza Zarrabi, Masoumeh Nouri, Masood Ghahvechi Akbari and 10 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Melika Jameie *Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-2028-9935
Neda Pak *Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mehrdad Mozafar *School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Hadis FarazmandDepartment of Radiology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Science, Tehran, Iran.
Elaheh KhodadoustR&D Department, Royan Stem Cell Technology Company, Tehran, Iran.
Anahita MajmaaDepartment of Pediatric Intensive Care, Pediatrics Center of Excellence, Children's Medical Center, Tehran, Iran.
Mobina AmanollahiTranslational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Morteza ZarrabiDepartment of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Masoumeh NouriR&D Department, Royan Stem Cell Technology Company, Tehran, Iran.
Masood Ghahvechi AkbariDepartment of Physical Medicine and Rehabilitation, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Ali Reza MoaiediDepartment of Pediatric Neurology, Clinical Research Development Center of Children's Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Reza Shervin BadvDepartment of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Massoud VosoughDepartment of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.
Amir Ali HamidiehPediatric Hematology, Oncology and Stem Cell Transplantation Department, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Hadi MontazerlotfelahiAlborz University of Medical Sciences, Karaj, Iran.
Ali Reza TavasoliDepartment of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Morteza HeidariDepartment of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Safdar MasoomiDepartment of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Fatemeh ZamaniAdvanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, Iran. doctorzamani@gmail.com.
Mahmoud Reza AshrafiDepartment of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. ashrafim@tums.ac.ir.ORCID http://orcid.org/0000-0001-5483-6549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cell therapies have shown promise in cerebral palsy (CP). However, their effects on brain metabolites, measured by proton magnetic resonance spectroscopy (

Indexed as

BrainCerebral PalsyMesenchymal Stem Cell TransplantationMetabolomeAspartic AcidChildChild, PreschoolCholineCreatineFemaleHumansMagnetic Resonance SpectroscopyMaleMesenchymal Stem CellsTreatment OutcomeAspartic AcidCholineCreatineN-acetylaspartateCerebral palsyCord blood stem cell transplantationMagnetic resonance spectroscopyMesenchymal stem cellStem cell researchStem cell transplantation

Identifiers

PMID42156830
PMCPMC13486729

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.