ArticleMethods in molecular biology (Clifton, N.J.)2026
Investigating Peptide-Lipid Membrane Interactions Using Small Angle X-Ray and Neutron Scattering.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Many structural characterization techniques either require a solid sample or for the sample to be placed on a substrate. This can be a challenge when the structure depends on the concentration of environmental parameters such as pH and salt. Small-angle X-ray/neutron scattering (SAXS/SANS) is an excellent tool that can be used for in situ, non-invasive, structural characterization of soft matter and biological systems in solution. In this chapter, we present how to prepare lipid vesicles as a relevant model system for cell membranes and their interactions with surface-active agents. We include a brief introduction of scattering theory and the basics of SAXS/SANS, how to analyze and interpret the data, as well as discussing some complementary techniques that can elucidate different aspects/properties of your sample.
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