Evidence map›Paper›PMID 42156641›Full record

ArticleOphthalmology and therapy2026

Summary of Research: Economic Benefit of Aflibercept 8 mg Versus Faricimab for Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema in the US.

Andreas Kuznik, Anna Coughlan, Amy Pinsent, Hector Toro-Diaz, Steven Sherman, Nimesh A Patel

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andreas KuznikHealth Economics and Outcomes Research, Regeneron Pharmaceuticals, Inc., Rockwood Road, Sleepy Hollow, Tarrytown, NY, 10591, USA. andreas.kuznik@regeneron.com.
Anna CoughlanPPD Evidera Health Economics & Market Access, Thermo Fisher Scientific, Wilmington, NC, USA.
Amy PinsentPPD Evidera Health Economics & Market Access, Thermo Fisher Scientific, London, UK.
Hector Toro-DiazPPD Evidera Health Economics & Market Access, Thermo Fisher Scientific, Wilmington, NC, USA.
Steven ShermanHealth Economics and Outcomes Research, Regeneron Pharmaceuticals, Inc., Rockwood Road, Sleepy Hollow, Tarrytown, NY, 10591, USA.
Nimesh A PatelHarvard Medical School, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This is a summary of the original article "Economic Benefit of Aflibercept 8 mg Versus Faricimab for Neovascular Age-Related Macular Degeneration or Diabetic Macular Edema in the US". Aflibercept 8 mg and faricimab are medications given by injections into the eye for treating the eye diseases neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). Comparing costs of these medications is important for patients, healthcare practitioners, and the people who pay for medications (payers). This research used an economic model to compare the estimated costs of aflibercept 8 mg and faricimab over 5 years in the United States, based on numbers of injections given in clinical trials. The analysis indicated that the lower number of injections needed for aflibercept 8 mg would lead to lower costs compared with faricimab for patients with nAMD or DME, which could benefit patients, healthcare providers, and payers.

Indexed as

AfliberceptAnti-VEGF therapyCostsFaricimab

Identifiers

PMID42156641
PMCPMC13315357

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.