Evidence map›Paper›PMID 42156565›Full record

ArticleCurrent microbiology2026

One Health Genomic Perspective on Pseudescherichia vulneris: A Neglected Reservoir of Last-Resort Resistance Genes.

Anelise S Ballaben, Julia M Cabrera, Leandro M Moreira, Mick Chandler, Alessandro M Varani

Abstract read
In one paragraph

Article in Current microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anelise S BallabenDepartment of Agricultural and Environmental Biotechnology, Faculty of Agricultural and Veterinary Sciences, Sao Paulo State University, Jaboticabal, SP, Brazil.
Julia M CabreraDepartment of Agricultural and Environmental Biotechnology, Faculty of Agricultural and Veterinary Sciences, Sao Paulo State University, Jaboticabal, SP, Brazil.
Leandro M MoreiraLaboratory of Genomics and Bacteria-Environment Interaction, Department of Biological Sciences, Institute of Exact and Biological Sciences, Federal University of Ouro Preto, Ouro Preto, MG, Brazil.
Mick ChandlerDepartment of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, USA.
Alessandro M VaraniDepartment of Agricultural and Environmental Biotechnology, Faculty of Agricultural and Veterinary Sciences, Sao Paulo State University, Jaboticabal, SP, Brazil. alessandro.varani@unesp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance (AMR) is a critical global threat, often driven by horizontal gene transfer mediated by mobile genetic elements (MGEs) such as plasmids, transposons, and integrons. Among Enterobacterales, IncHI2/IncHI2A plasmids are of particular concern, as they combine broad host range, conjugative potential, and mosaic architecture enriched with antimicrobial resistance genes (ARGs), biocide tolerance, and heavy-metal resistance. This study provides the first systematic comparative genomics of Pseudescherichia vulneris, an underrecognized yet genomically versatile species at the human-animal-environment interface. All 30 publicly available genomes were analyzed to reconstruct the pangenome, resistome, virulome, and associated MGEs. The pangenome was open, reflecting ongoing diversification and strong potential for horizontal gene acquisition. Resistomes were highly heterogeneous, ranging from minimal repertoires in most animal and environmental isolates to multidrug-resistance profiles in hospital-associated and occasional animal genomes. Clinically significant determinants, including bla

Indexed as

Drug Resistance, BacterialDrug Resistance, Multiple, BacterialEnterobacteriaceaeGenome, BacterialAnimalsAnti-Bacterial AgentsDNA Transposable ElementsEnterobacteriaceae InfectionsGene Transfer, HorizontalGenomicsHumansInterspersed Repetitive SequencesOne HealthPlasmidsAnti-Bacterial AgentsDNA Transposable Elements

Identifiers

PMID42156565
PMCPMC13186809

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.