ArticleNature communications2026
A modular multi-color fluorescence microscope for simultaneous tracking of cellular activity and behavior.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- An epifluorescence microscope design for naturalistic behavior and cellular activity in freely moving Caenorhabditis elegans.Nature communications · 2026Article
- Article
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Authors and funding
6 authors.
Funding
Abstract
We present a modular epifluorescence tracking microscope which enables ratiometric imaging of muscles, neurons, and other structures in moving animals. The microscope is assembled entirely from commercial parts within 3 h, making the system broadly accessible. Leveraging the improved brightness and bleaching characteristics of recent genetically encoded indicators and fluorophores, the simple microscope is even suitable for calcium imaging of neurons in behaving animals, as we demonstrate in C. elegans. We also show how muscle dynamics in D. melanogaster larvae can be analyzed and how dual color fluorescence tracking elucidates inter-species interactions by visualizing both predatory nematodes and their prey. Finally, we showcase a configuration for brightfield imaging by tracking tardigrade gait as an example of utility for non-labeled species. The affordability of the hardware and ease of use of the accompanying software make this a suitable tool for education in addition to its use in research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.