Evidence map›Paper›PMID 42155862›Full record

ArticleAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2026

Predictors of psychosocial burden in parents of children with food allergy.

Stephanie A Kubala, Fernanda D Young, Viviane Callier, Marjohn M Rasooly, Caeden Dempsey, Allyson Mateja, Erica Brittain, Pamela A Frischmeyer-Guerrerio

Registry-linked trialAbstract read
In one paragraph

Article in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02504853 (Natural History and Genetics of Food Allergy and Related Conditions), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02504853 recruitingnot on this map

Natural History and Genetics of Food Allergy and Related Conditions

TypeobservationalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2015 to 2027Enrolled1,800ConditionsFood Allergy, Loeys-Dietz Syndrome, Atopic Dermatitis, Eosinophilic Esophagitis
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie A KubalaFood Allergy Research Section, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, Maryland.
Fernanda D YoungFood Allergy Research Section, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, Maryland.
Viviane CallierClinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland.
Marjohn M RasoolyFood Allergy Research Section, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, Maryland.
Caeden DempseyFood Allergy Research Section, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, Maryland.
Allyson MatejaClinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Frederick, Maryland.
Erica BrittainBiostatistics Research Branch, National Institute of Allergy and Infectious Diseases/National Institutes of Health, North Bethesda, Maryland.
Pamela A Frischmeyer-GuerrerioFood Allergy Research Section, National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, Maryland. Electronic address: pamela.guerrerio@nih.gov.

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI PENDLETON, RICHARD · 2019 to 2025
$3932.6M
Pathogenesis of Food AllergyZIAAI001202 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI FRISCHMEYER-GUERRERIO, PAMELA · 2015 to 2025
$10.2M
Intramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI001202NIH HHS 75N91019D00024
6 · The paper itself

Abstract

backgroundThe psychosocial burden of food allergy (FA) impacts the entire family, particularly the affected child and their parents.

objectiveTo evaluate psychosocial parental burden (PB) in families of children with FA, identify factors associated with PB, and assess its relationship with child-reported and parent-proxy food allergy quality of life (FAQOL).

methodsA total of 114 children aged 2 to 17 years with IgE-mediated FA and their parents (mothers = 86.5%) completed validated age-specific FAQOL and PB questionnaires. Associations between demographic and clinical variables and scores were analyzed.

resultsGreater PB was associated with more frequent and/or severe reactions, reactions to trace allergen exposures, multiple FAs, wheat or unbaked milk or egg allergy, and/or a history of oral food challenge (regardless of outcome). Strict allergen avoidance practices were associated with worse PB; a parent working in healthcare was associated with better PB. The age, sex, ethnicity, and/or race of the child had no significant association. The PB scores correlated with FAQOL scores in children younger than 13 years, but not in children aged 13 years and older. Where both parental-proxy FAQOL and self-reported child FAQOL forms were available (age 8-12 years), scores were similar for questions pertaining to allergen avoidance and dietary restrictions, but parents reported less emotional impact of FA on their children than the children themselves reported.

conclusionThe number and severity of reactions, the type and number of FA, parents in the medical profession, and avoidance practices are associated with impacts on PB. The psychosocial well-being of parents was correlated with that of their children until age 13 years, but not after. Parents may underestimate the emotional impact of FA on their older children.

trial registrationClinicalTrials.gov Identifier: NCT02504853; Natural History and Genetics of Food Allergy and Related Conditions; https://clinicaltrials.gov/study/NCT02504853.

Indexed as

Cost of IllnessFood HypersensitivityParentsQuality of LifeAdolescentAllergensChildChild, PreschoolFemaleHumansMaleSurveys and QuestionnairesAllergens

Identifiers

PMID42155862
PMCPMC13276776

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.