ArticleNeurotoxicology and teratology
Evidence of decreased neural efficiency supporting fluid reasoning abilities in children and adolescents chronically exposed to home radon.
Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Fluid reasoning (Gf), the ability to solve novel problems without prior knowledge, is a highly integrative skill with far-reaching impacts on multiple domains of functioning including attention and working memory. Gf abilities like abstract reasoning rapidly develop throughout childhood and adolescence in tandem with the maturation of underlying functional brain networks. With such dynamic plasticity, these networks are also critically vulnerable to the neurotoxic effects of environmental exposures. Herein, we characterized the links between chronic exposure to indoor radon, a ubiquitous toxin that commonly remains unmitigated, and the neural dynamics supporting Gf. A total of 101 neurotypical youth ages 8-to-15 years-old (M = 12.34 ± 2.23 years; 51 males) completed an abstract reasoning task during magnetoencephalography and completed a long-term home radon test to quantify home radon concentrations. We found that as a function of greater home radon exposure, youth were significantly slower to respond during the abstract reasoning task (b = 45.88, p = .047). Further, youth exhibited stronger theta responses in the right superior temporal gyrus (β = 0.33, p = .002), and stronger alpha/beta responses in the right medial prefrontal cortex (β = -0.36, p < .001) with greater radon exposure. The data suggested an overall pattern of radon-related neural inefficiency when engaging in Gf processing, which could have long-term impacts on extended neurocognitive outcomes. These findings highlight the importance of continued study of the potential neurotoxic effects of chronic home radon exposure on youth, and reiterate the need for greater public awareness regarding indoor radon safety.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.