Evidence map›Paper›PMID 42154903›Full record

ArticleRevista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria2026

Efficacy of Metarhizium spp. against gastrointestinal nematodes in goats and evidence of conidia infection through the integument.

Ially de Almeida Moura, Antônio Wesley Oliveira da Silva, Mayara Macêdo Barrozo, Thaís Almeida Corrêa, Patrícia Silva Gôlo, Isabele da Costa Ângelo, Caio Márcio de Oliveira Monteiro, Éverton Kort Kamp Fernandes, Vânia Rita Elias Pinheiro Bittencourt, Alexandre Dias Munhoz and 1 more

Abstract read
In one paragraph

Article in Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ially de Almeida MouraUniversidade Estadual de Santa Cruz - UESC, Departamento de Ciências Agrárias e Ambientais, Ilhéus, BA, Brasil.ORCID http://orcid.org/0000-0002-7912-2419
Antônio Wesley Oliveira da SilvaUniversidade Federal da Bahia - UFBA, Programa de Ciência Animal nos Trópicos, Salvador, BA, Brasil.
Mayara Macêdo BarrozoUniversidade Federal de Goiás - UFG, Departamento de Biociências e Tecnologia do Instituto de Patologia Tropical e Saúde Pública, Goiánia, Goiás, Brasil.
Thaís Almeida CorrêaUniversidade Federal Rural do Rio de Janeiro - UFRRJ, Instituto de Veterinária, Departamento de Parasitologia Animal, Seropédica, RJ, Brasil.
Patrícia Silva GôloUniversidade Federal Rural do Rio de Janeiro - UFRRJ, Instituto de Veterinária, Departamento de Parasitologia Animal, Seropédica, RJ, Brasil.
Isabele da Costa ÂngeloUniversidade Federal Rural do Rio de Janeiro - UFRRJ, Instituto de Veterinária, Departamento de Parasitologia Animal, Seropédica, RJ, Brasil.
Caio Márcio de Oliveira MonteiroUniversidade Federal de Goiás - UFG, Departamento de Biociências e Tecnologia do Instituto de Patologia Tropical e Saúde Pública, Goiánia, Goiás, Brasil.
Éverton Kort Kamp FernandesUniversidade Federal de Goiás - UFG, Departamento de Biociências e Tecnologia do Instituto de Patologia Tropical e Saúde Pública, Goiánia, Goiás, Brasil.
Vânia Rita Elias Pinheiro BittencourtUniversidade Federal Rural do Rio de Janeiro - UFRRJ, Instituto de Veterinária, Departamento de Parasitologia Animal, Seropédica, RJ, Brasil.
Alexandre Dias MunhozUniversidade Estadual de Santa Cruz - UESC, Departamento de Ciências Agrárias e Ambientais, Ilhéus, BA, Brasil.
Wendell Marcelo de Souza PerinottoUniversidade Federal Rural do Rio de Janeiro - UFRRJ, Instituto de Veterinária, Departamento de Parasitologia Animal, Seropédica, RJ, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The search for sustainable alternatives to manage gastrointestinal nematodes in small ruminants has intensified due to rising anthelmintic resistance. This study evaluated in vitro the efficacy of several Brazilian isolates of the genus Metarhizium spp. on gastrointestinal nematodes (GINs) of goats which were naturally infected with mixed populations predominantly composed of Haemonchus spp. (63%), Trichostrongylus spp. (35%), and Oesophagostomum spp. (2%). Biological assays were conducted using quantitative coproculture after 10 days of incubation, and SEM was performed after 72 h of fungus-larva interaction. Isolates LCM S05, LCM S10, LCM S11, LCM S13, LCM S14, and LCM S15 promoted larval reduction of: 50.24%, 43.29%, 44.99%, 55.45%, 52.52%, and 67.95%, respectively. Isolate LCM S15, which showed the greatest reduction in larvae, was tested at concentrations of 1.0 × 106, 1.0 × 107, and 1.0 × 108 conidia/mL, resulting in reductions in larvae of 36.90%, 50.17%, and 68.28%, respectively. In SEM, photomicrographs demonstrated that conidia adhered to and germinated on the nematode integument. This study demonstrates the potential of Brazilian isolates of Metarhizium spp. for the control of GINs in goats and highlights the route of fungal infection through the integument.

Indexed as

Goat DiseasesMetarhiziumNematodaNematode InfectionsSpores, FungalAnimalsGoats

Identifiers

PMID42154903
PMCPMC13193326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.