Evidence map›Paper›PMID 42154894›Full record

ArticleEuropean journal of public health2026

Alcohol consumption, smoking, and weight loss outcomes: findings from a 12-month digital lifestyle intervention.

Emma R Wu, Anu Joki, Mikko S Venäläinen, Laura-Unnukka Suojanen, Kirsi H Pietiläinen, Aila J Ahola

Registry-linked trialAbstract readClinical Study
In one paragraph

Article in European journal of public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04019249 (HealthyWeightHub.fi), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04019249 narecruitingnot on this map

HealthyWeightHub.fi: Web-based Management of Obesity in a Real-life Clinical Setting

TypeinterventionalSponsorHelsinki University Central HospitalRan2016 to 2030Enrolled6,000ConditionsObesityArmsHealthy Weight Coaching
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emma R WuUniversity of South Florida Morsani College of Medicine, Tampa, FL, United States.ORCID 0009-0002-6519-6043
Anu JokiObesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-7814-2186
Mikko S VenäläinenDepartment of Medical Physics, Turku University Hospital and University of Turku, Turku, Finland.ORCID 0000-0003-1777-4259
Laura-Unnukka SuojanenHealthy Weight Hub, Abdominal Centre, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0003-0771-8026
Kirsi H PietiläinenObesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-8522-1288
Aila J AholaObesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5200-4597

Funding

Academy of Finland 266286Academy of Finland 272376Academy of Finland 314383Academy of Finland 335443Academy of Finland 369181Finnish Diabetes Research FoundationFinnish Foundation for Cardiovascular ResearchFinnish Medical FoundationGovernment Research FundsGyllenberg FoundationNovo Nordisk Foundation NNF10OC1013354Novo Nordisk Foundation NNF17OC0027232Novo Nordisk Foundation NNF20OC0060547Novo Nordisk Foundation NNF24OC0091683Novo Nordisk Foundation NNF25SA0103783Paulo FoundationSigrid Jusélius FoundationUniversity of Helsinki and Helsinki University Hospital
6 · The paper itself

Abstract

To investigate associations between alcohol consumption, smoking, and weight loss outcomes over a 12-month digital lifestyle intervention, the Healthy Weight Coaching. Weight, height, and waist circumference were self-reported at baseline, followed by weekly weight and quarterly waist circumference reporting. Interpolated weights were used to calculate body mass index at 3, 6, 9, and 12 months. At these timepoints, relative changes from baseline in weight and waist circumference were calculated. On web-based questionnaires, participants reported alcohol consumption (frequency, single-session dose) and smoking (status, daily dose, start age, end year). Participants were categorized as abstinent, low-risk drinkers, and risky drinkers (men: >14 units/week or >6 units/occasion; women: >7 units/week or >5 units/occasion), and as current, former and non-smokers. At baseline, of the 1719 participants (83.3% women, median age 51 years, body mass index 39.1 kg/m2), 20.9% reported abstinence and 16.2% risky drinking, while 12.1% and 22.3% were current and former smokers, respectively. Alcohol consumption decreased over the program, driven by reductions among baseline risky drinkers. Among baseline non-drinkers, increased alcohol intake over 12 months was linked to smaller waist circumference reduction (weekly dose, B = 0.762, P = 0.005; single-session dose, B = 1.168, P = 0.020). Instead, among baseline risky drinkers, cutting alcohol intake was linked to greater weight loss (weekly dose, B = 0.062, P = 0.034; single-session dose, B = 0.321, P < 0.001), and larger waist circumference reduction (single-session dose, B = 0.381, P = 0.031). Higher number of pack-years was associated with attenuated waist circumference reduction (B = 0.059, P = 0.002). Addressing alcohol consumption and smoking may improve weight loss outcomes in digital lifestyle interventions. The trial is registered at clinicaltrials.gov (Clinical Trials Identifier NCT04019249).

Indexed as

Alcohol DrinkingLife StyleSmokingWeight LossAdultBody Mass IndexFemaleHumansMaleMiddle AgedSurveys and QuestionnairesWaist Circumference

Identifiers

PMID42154894
PMCPMC13186192

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.