ArticleArquivos de gastroenterologia2026
LONG-TERM QUALITY OF LIFE AFTER ILEAL POUCH-ANAL ANASTOMOSIS FOR ULCERATIVE COLITIS IN A BRAZILIAN IBD REFERRAL CENTER.
Article in Arquivos de gastroenterologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundReports on the long-term impact on quality of life (QoL) after ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) are scarce in Latin America.
objectiveTo evaluate QoL after IPAA in an inflammatory bowel disease (IBD) referral center in Brazil.
methodsFrom March 2023 to August 2023, a standardized questionnaire was administered to patients with UC who had previously undergone IPAA surgery. The questionnaire addressed: (1) daily bowel movement frequency, (2) daytime and nighttime fecal incontinence, (3) need for daily medication such as loperamide, (4) fecal urgency, (5) social limitations, (6) fatigue, (7) impact on sexual life, (8) use of diapers, and (9) impact on work ability.
resultsIn total, 28 patients completed the questionnaire. Most patients were female (19, 67.9%), with a mean age of 44.8±10.2 years and an average follow-up time of 13.8 years. Patients reported an average of 6.0±1.8 bowel movements per day, with 27 (96.4%) experiencing diarrhea. Diaper use was generally unnecessary (22, 78.6%). Most patients had nocturnal bowel movements (24, 85.7%) and fecal urgency (17, 60.7%). Antidiarrheal medication (loperamide) was required by 21 patients (75%) to reduce bowel movement frequency. Despite high satisfaction levels with IPAA (22, 78.6%), patients reported negative impacts on bowel habits and several QoL domains, including fatigue (27, 96.4%), sexual life (18, 64.3%), social and work activities (22, 78.6%), and feelings of shame (21, 75%). However, dietary restrictions were minimal (17, 60.7%).
conclusionAlthough long-term satisfaction with IPAA is high, patients experience significant negative impacts on bowel habits and QoL. These findings underscore the need for targeted strategies to improve outcomes and support for future IPAA patients.
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