ArticleProceedings of the National Academy of Sciences of the United States of America2026
Pneumococcal membrane particles promote serotype-independent cellular and humoral immunity and protect against pneumococcal colonization.
Rebecca Dookie, Ana Rita Narciso, Meztlli O Gaytán, Anandi Narayana Moorthy, Sayoni Chakraborty, Sigrun Thorsdottir, John Boss, Francesco Righetti, Jens Karlsson, Max Heurgren and 2 more
Abstract read
In one paragraphArticle in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Rebecca DookieDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.ORCID 0000-0001-7850-2543 Ana Rita NarcisoDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.ORCID 0000-0003-1316-3856 Meztlli O GaytánDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.ORCID 0000-0003-3636-1919 Anandi Narayana MoorthyDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.
Sayoni ChakrabortyDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.
Sigrun ThorsdottirDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.
John BossDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.
Francesco RighettiDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.
Jens KarlssonDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.ORCID 0000-0002-8005-9197 Max HeurgrenDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.
Staffan NormarkDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.ORCID 0000-0001-7917-3921 Birgitta Henriques-NormarkDepartment of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Stockholm 171 65, Sweden.ORCID 0000-0002-5429-4759 Funding
Knut and Alice Wallenberg Foundation KAW2022.0227Region Stockholm FoUI-985773The Swedish Foundation for Strategic research (SSF) RMX18-0041 007The Swedish Research Council 2018-05798; 2020-01342;2021-02059;2023-01975;Torsten Soderberg Foundation Akademiprofessur
6 · The paper itselfAbstract
Despite implementation of pneumococcal conjugated vaccines (PCVs) against
Indexed as
Immunity, CellularImmunity, HumoralPneumococcal InfectionsPneumococcal VaccinesStreptococcus pneumoniaeAnimalsAntigens, BacterialExtracellular VesiclesFemaleHumansImmunizationInterleukin-17MiceMice, Inbred C57BLSerogroupTh17 CellsAntigens, BacterialInterleukin-17Pneumococcal VaccinesToll-Like Receptor 2membrane particlesmucosal immune responsepneumococcal colonizationpneumococcal infectionsvaccine
Identifiers
PMID42154558
PMCPMC13214003
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390