Evidence map›Paper›PMID 42154294›Full record

ArticleMarine biotechnology (New York, N.Y.)2026

Bioactive Extracts from Yucatán Marine Invertebrates as Modulators of Microalgal Dynamics.

Dawrin Pech-Puch, Rita Pires, Bárbara A Rebelo, Diana Grilo, Carlos Gonzáles-Salas, Susana Eunice Calva-Pérez, Susana M Gomes, Harold Villegas-Hernández, Sergio Guillén-Hernández, Abel M Forero and 4 more

Abstract read
In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dawrin Pech-Puch *Escuela Nacional de Estudios Superiores Unidad Mérida (ENES Mérida), Universidad Nacional Autónoma de México (UNAM), Carretera Mérida-Tetiz km 4.5, Tablaje, Catastral No. 6998, Municipio de Ucú, Ucú, CP 97357, Merida, Mexico.
Rita Pires *Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA), Universidade Nova de Lisboa, Lisbon, Portugal.
Bárbara A Rebelo *Instituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA), Universidade Nova de Lisboa, Lisbon, Portugal.
Diana GriloInstituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA), Universidade Nova de Lisboa, Lisbon, Portugal.
Carlos Gonzáles-SalasDepartamento de Biología Marina, Universidad Autónoma de Yucatán, Km. 15.5, Carretera Mérida-Xmatkuil, A.P. 4-116 Itzimná, Merida, CP 97100, Mexico.
Susana Eunice Calva-PérezEscuela Nacional de Estudios Superiores Unidad Mérida (ENES Mérida), Universidad Nacional Autónoma de México (UNAM), Carretera Mérida-Tetiz km 4.5, Tablaje, Catastral No. 6998, Municipio de Ucú, Ucú, CP 97357, Merida, Mexico.
Susana M GomesInstituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA), Universidade Nova de Lisboa, Lisbon, Portugal.
Harold Villegas-HernándezDepartamento de Biología Marina, Universidad Autónoma de Yucatán, Km. 15.5, Carretera Mérida-Xmatkuil, A.P. 4-116 Itzimná, Merida, CP 97100, Mexico.
Sergio Guillén-HernándezDepartamento de Biología Marina, Universidad Autónoma de Yucatán, Km. 15.5, Carretera Mérida-Xmatkuil, A.P. 4-116 Itzimná, Merida, CP 97100, Mexico.
Abel M ForeroCentro de Interdisciplinar de Química e Bioloxía (CICA), Facultade de Ciencias, Universidade da Coruña, 15071, A Coruña, Spain.
Jaime RodriguezCentro de Interdisciplinar de Química e Bioloxía (CICA), Facultade de Ciencias, Universidade da Coruña, 15071, A Coruña, Spain.
Carlos JiménezCentro de Interdisciplinar de Química e Bioloxía (CICA), Facultade de Ciencias, Universidade da Coruña, 15071, A Coruña, Spain. carlos.jimenez@udc.es.
Oscar A Lenis-RojasInstituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA), Universidade Nova de Lisboa, Lisbon, Portugal. oscar.rojas@itqb.unl.pt.
Rita AbranchesInstituto de Tecnologia Química e Biológica António Xavier (ITQB NOVA), Universidade Nova de Lisboa, Lisbon, Portugal. ritaa@itqb.unl.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The marine environment is a rich source of bioactive compounds with a wide range of applications. In this study, 65 extracts from sponges, ascidians, and a gorgonian collected from the Yucatán Peninsula, Mexico, were evaluated for their modulatory effects on the growth of four microalgal species. Some extracts were found to exhibit pronounced algicidal activity, while others promoted growth. Bioassay-guided fractionation of the extract from Haliclona (Rhizoniera) curacaoensis led to the identification of arenosclerins A and C as potent algicidal agents, active across all tested microalgae. In contrast, the extract from Halichondria melanadocia enhanced microalgal growth, and chemical analysis revealed the presence of medelamine A and B as putative growth-promoting compounds. This study provides a new report on microalgae-modulating activities of marine sponge metabolites. The dual activity observed, both inhibitory and stimulatory, not only contributes to our understanding of marine compound diversity but also underscores the potential of these marine-derived compounds for sustainable environmental management practices.

Indexed as

MicroalgaePoriferaUrochordataAnimalsHaliclonaMexicoAlgicidalArenosclerin A and CBioactive compoundsHalichondria melanadociaHaliclona (Rhizoniera) curacaoensisSpongesStimulants

Identifiers

PMID42154294
PMCPMC13186800

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.