Evidence map›Paper›PMID 42154203›Full record

Observational studyIndian pediatrics2026

Incidence and Independent Risk Factors of Central Venous Catheter-Related Thrombosis in Critically Ill Children: A Prospective Study in Vietnam.

Duc Van Mai, Phi Duong Nguyen, Thy Vu Phuong Le, An Thi Thanh Dao

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Indian pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Duc Van MaiDepartment of Pediatrics, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0009-0002-5954-6211
Phi Duong NguyenOrthopaedic-Burn-Plastic Surgery Department, City Children's Hospital, Ho Chi Minh City, Vietnam.
Thy Vu Phuong LePediatric Intensive Care Unit, City Children's Hospital, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0009-0008-3387-3154
An Thi Thanh DaoDepartment of Pediatrics, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. daothithanhan@ump.edu.vn.ORCID http://orcid.org/0000-0002-9556-4049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the incidence and identify independent risk factors of central venous catheter (CVC)-related thrombosis in critically ill children admitted to a pediatric intensive care unit in a middle-income country, and to contribute context-specific prospective data relevant to clinical practice.

methodsIn this prospective observational study, catheterization episodes in children undergoing central venous catheter (CVC) placement were systematically screened with Doppler ultrasonography within 24-48h after insertion and weekly thereafter. Clinical and catheter-related variables were analyzed using multivariable generalized estimating equation models with a logit link to identify independent predictors of catheter-associated thrombosis.

resultsA total of 129 catheters, including 105 infusion catheters and 24 hemodialysis catheters, corresponding to 111 catheterization episodes were evaluated in 103 children. Thrombotic events related to CVCs occurred in 22 of 111 catheterization episodes (19.8%). In the overall cohort, multivariate generalized estimating equation analysis identified a history of thrombosis as an independent predictor of CVC-related thrombosis. In the infusion catheter subgroup, femoral vein CVC placement and catheter dwell time > 7 days were additional independent risk factors.

conclusionsApproximately one in five catheterization episodes in critically ill children was associated with thrombosis. History of thrombosis was an independent predictor overall; femoral vein CVC placement and CVC dwell time > 7 days were significant in the infusion catheter subgroup. These findings emphasize the need for risk-adapted ultrasound surveillance and careful catheter management in high-acuity, resource-limited pediatric intensive care settings.

Indexed as

Catheterization, Central VenousCentral Venous CathetersCritical IllnessThrombosisAdolescentChildChild, PreschoolFemaleHumansIncidenceInfantIntensive Care Units, PediatricMaleProspective StudiesRisk FactorsUltrasonography, DopplerCentral venous cathetersCritical illnessPediatric intensive care unitsRisk factorsVenous thrombosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.