ArticleJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]2026
Assessment of Monomer Release From Resin Composites Following the Use of Various Modeling Liquids.
Article in Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe chemical composition of resin composites and the use of modeling liquids may influence the release of residual monomer, potentially impacting biocompatibility. This in vitro study evaluated the effect of different modeling liquids on the elution of monomers from two resin composites. MATERIALS AND
methodsEighty disc-shaped samples were prepared using two nano-hybrid resin composites (Estelite Sigma Quick, Tokuyama; Harmonize, KERR) and three modeling liquids; Composite Wetting Resin (Ultradent, USA), Modeling Resin (Bisco, USA), and Modeling Liquid (GC, Japan) (n = 10). Resin composites were placed in four 0.5-mm increments into Teflon molds, and modeling liquids were applied with a brush between layers; control groups were prepared without modeling liquids. After polishing (Sof-Lex, 3 M ESPE), specimens were stored in 75% ethanol at 37°C. Release of UDMA, Bis-GMA, TEGDMA, and HEMA was quantified using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) system (LCMS-8050, Shimadzu, Japan) at 24 h, 7 days, and 30 days. Data normality was assessed, and effects of resin composites type, modeling liquid, and time were analyzed using three-way ANOVA with Bonferroni post hoc testing (α = 0.05).
resultsApplication of modeling liquid significantly reduced Bis-GMA release for both resin composites (p < 0.05). While TEGDMA release was significantly decreased in Estelite Sigma Quick groups (p < 0.05), no difference was observed in Harmonize groups. Modeling liquid applications increased total HEMA and UDMA release (p < 0.05). TEGDMA release in the Estelite Sigma Quick-control group was higher than the Harmonize-control group (p < 0.05).
conclusionThe organic matrix of composite resins and the modeling liquids used influence the release of the tested monomers (TEGDMA, BisGMA, UDMA, and HEMA). The use of modeling liquid showed differences in monomer release according to the content of the liquid. CLINICAL SIGNIFICANCE: Modeling liquids may increase residual monomer release from resin composites, particularly shortly after polymerization. Clinicians should use these materials sparingly and in accordance with manufacturers' instructions to minimize potential biocompatibility risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.