Evidence map›Paper›PMID 42154088›Full record

ReviewActa neurochirurgica2026

Elasticity-guided tumor resection: applying biomechanical information to neurosurgical practice.

Jan Saip Aunan-Diop, Bo Halle, Anca Friismose, Christian Bonde Pedersen, Mads Hjortdal Grønhøj, Emi Hojo, Ziying Yin, Christoffer Olsson, Rodrigo Moreno, Bo Mussmann and 1 more

Abstract readReview
In one paragraph

Review in Acta neurochirurgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jan Saip Aunan-DiopDepartment of Neurosurgery, Odense University Hospital, Odense, Denmark. j.s.d@hotmail.no.
Bo HalleDepartment of Neurosurgery, Odense University Hospital, Odense, Denmark.
Anca FriismoseDepartment of Radiology, Odense University Hospital, Odense, Denmark.
Christian Bonde PedersenDepartment of Neurosurgery, Odense University Hospital, Odense, Denmark.
Mads Hjortdal GrønhøjDepartment of Neurosurgery, Odense University Hospital, Odense, Denmark.
Emi HojoDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ziying YinDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Christoffer OlssonDivision of Biomedical Imaging, Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, Stockholm, Sweden.
Rodrigo MorenoDivision of Biomedical Imaging, Department of Biomedical Engineering and Health Systems, KTH Royal Institute of Technology, Stockholm, Sweden.
Bo MussmannDepartment of Radiology, Odense University Hospital, Odense, Denmark.
Frantz Rom PoulsenDepartment of Neurosurgery, Odense University Hospital, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor stiffness and adhesion are decisive factors in neurosurgical strategy, yet they remain absent from standard planning and navigation. Advances in biomechanics allow these properties to be measured and mapped across modalities: magnetic resonance elastography for preoperative stiffness and adhesion, intraoperative ultrasound elastography for real-time updates, and rheometry as biological ground truth. Emerging frameworks could integrate these measurements with artificial intelligence and multimodal neuroimaging to produce probabilistic maps of tumor consistency and brain-tumor interface quality. We define this concept as elasticity-guided neurosurgery: the incorporation of biomechanical parameters into surgical decision-making to improve safety, efficiency, and personalization. By transforming tactile impressions into actionable data, elasticity-guided neurosurgery could represent a paradigm shift toward more information-driven neurosurgical oncology.

Indexed as

Brain NeoplasmsElasticity Imaging TechniquesNeurosurgical ProceduresSurgery, Computer-AssistedBiomechanical PhenomenaHumansBiomechanicsBrain tumorElastographyNeurosurgeryViscoelasticity

Identifiers

PMID42154088
PMCPMC13357444

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.