Evidence map›Paper›PMID 42153993›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation.

Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kieran AbbottDepartment of Engineering, University of Cambridge, Cambridge, UK.
Georgeos HardoUnited Arab Emirates University, Al Ain, Abu Dhabi, UAE.
Ruizhe LiDepartment of Engineering, University of Cambridge, Cambridge, UK.
Jack BradleyDepartment of Engineering, University of Cambridge, Cambridge, UK.
Ashraf ZarkanDepartment of Genetics, University of Cambridge, Cambridge, UK.
Somenath BakshiDepartment of Engineering, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0003-3864-2546

Funding

Biotechnology and Biological Sciences Research Council BB/M011194/1Cambridge University Startup Award for Lectureship in Synthetic Biology NKXY ISSF3/46Engineering and Physical Sciences Research Council EP/W032813/1Isaac Newton Trust (21.22(a)iii)Rosetrees Trust JS16/TTI2021\1Transition To Independence (TTI) fellowship from the School of Biological Sciences at the University of CambridgeUniversity of Cambridge School of Technology Seed FundWellcome TrustWellcome Trust RG89305
6 · The paper itself

Abstract

Antibiotic treatment failure, often driven by non-genetic mechanisms such as tolerance and persistence, remains a major global health challenge.

Indexed as

Anti-Bacterial Agentsbeta-LactamsEscherichia coliStress, Physiologicalbeta Lactam AntibioticsSingle-Cell AnalysisTime-Lapse ImagingAnti-Bacterial Agentsbeta Lactam Antibioticsbeta-Lactamsantibiotic persistenceantibiotic pharmacokineticsrelapse dynamicssingle‐cell analysistransient tolerance

Identifiers

PMID42153993
PMCPMC13336005

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.