Evidence map›Paper›PMID 42153977›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Mastication-Induced Electrical Stimulation Activates Prg4

Shi-Yang Feng, Jing-Rong Cheng, Yu Qin, Jie Lei, Chen-Chen Gao, Hong-Ying Fu, Li-Ping Wu, Thanh D Nguyen, Xu-Liang Deng, Kai-Yuan Fu and 1 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shi-Yang FengCenter For TMD and Orofacial Pain, Peking University School and Hospital of Stomatology, Beijing, China.
Jing-Rong ChengNMPA Center for Innovation and Research in Regulatory Science and Beijing Key Laboratory of Digital Stomatology, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
Yu QinDepartment of Orthopedics, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-2128-9731
Jie LeiCenter For TMD and Orofacial Pain, Peking University School and Hospital of Stomatology, Beijing, China.ORCID https://orcid.org/0000-0002-3429-4436
Chen-Chen GaoCenter For TMD and Orofacial Pain, Peking University School and Hospital of Stomatology, Beijing, China.
Hong-Ying FuNMPA Center for Innovation and Research in Regulatory Science and Beijing Key Laboratory of Digital Stomatology, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
Li-Ping WuNMPA Center for Innovation and Research in Regulatory Science and Beijing Key Laboratory of Digital Stomatology, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.
Thanh D NguyenDepartment of Biomedical Engineering, University of Connecticut, Storrs, Connecticut, USA.ORCID https://orcid.org/0000-0003-0813-4807
Xu-Liang DengNMPA Center for Innovation and Research in Regulatory Science and Beijing Key Laboratory of Digital Stomatology, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.ORCID https://orcid.org/0000-0003-1838-6274
Kai-Yuan FuCenter For TMD and Orofacial Pain, Peking University School and Hospital of Stomatology, Beijing, China.
Yang LiuNMPA Center for Innovation and Research in Regulatory Science and Beijing Key Laboratory of Digital Stomatology, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.

Funding

Beijing Natural Science Foundation 7254456Hainan Provincial Natural Science Foundation of China 825MS196National Key R&D Project of China, Ministry of Science and Technology of the People's Republic of China 2023YFC2509200National Natural Science Foundation of China 52273258National Natural Science Foundation of China 52303171National Natural Science Foundation of China 82170979National Natural Science Foundation of China 82201091National Natural Science Foundation of China 82221003
6 · The paper itself

Abstract

Osteoarthritis (OA) is a whole-joint degenerative disease primarily driven by excessive mechanical overloading, yet current therapies fail to harness biomechanical cues to halt cartilage degeneration. Here, we developed mastication-driven magnesium-incorporated piezoelectric nanofibers (MagPie) that could convert joint loading into localized electrical stimulation while releasing Mg

Indexed as

ChondrocytesElectric StimulationOsteoarthritisProteoglycansAnimalsDisease Models, AnimalMaleProteoglycan 4RatsRats, Sprague-DawleyProteoglycan 4Proteoglycanscartilage regenerationosteoarthritispiezoelectrical stimulationsingle‐cell RNA‐sequencing

Identifiers

PMID42153977
PMCPMC13336053

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.