ArticleJACC. Case reports2026
High-Grade Serous Ovarian Carcinoma Presenting as Cardiac Tamponade.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
backgroundWe present a case report of ovarian carcinoma with pericardial metastasis causing echocardiographic tamponade. CASE SUMMARY: A woman in her 70s with breast cancer gene 1 (BRCA1), B7-H4 positive, high-grade serous ovarian carcinoma with metastasis to the lungs presented with subacute dyspnea. Echocardiogram showed a large, circumferential pericardial effusion of 2.5 cm with tamponade physiology. Emergent pericardiocentesis yielded 420 mL of serosanguinous fluid. Cytology of the pericardial fluid was consistent with metastatic adenocarcinoma of ovarian origin. The patient pursued hospice care, where she later died. DISCUSSION: Ovarian carcinomas rarely metastasize above the diaphragm or to the heart. Few cases have been reported on cytology-positive high-grade serous ovarian carcinoma from pericardial fluid of a patient presenting with tamponade. TAKE-HOME MESSAGE: A pericardial effusion is the most common manifestation of ovarian cancer metastatic to the heart.
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