Evidence map›Paper›PMID 42153809›Full record

ReviewMedicine2026

Acute fluoroacetamide poisoning with reversible leukoencephalopathy: A case report and literature review highlighting the effectiveness of acetamide and the diagnostic value of neuroimaging.

Zhongliang Xu, Shaopeng Ma, Zhuangfei Li, Shengkun Yang, Deyu Yang, Zhengze Shen, Shudong Liu

Abstract readCase ReportsReview
In one paragraph

Review in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhongliang XuDepartment of Pharmacy, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing Municipal, P. R. China.ORCID 0000-0001-7023-3756
Shaopeng MaDepartment of Neurology, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing Municipal, P. R. China.
Zhuangfei LiDepartment of Pharmacy, Maternal and Child Health Hospital of Yongchuan District, Chongqing Municipal, P. R. China.
Shengkun YangDepartment of Neurology, Sanjiao Town Health Center of Yongchuan District, Chongqing Municipal, P. R. China.
Deyu YangDepartment of Neurology, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing Municipal, P. R. China.
Zhengze ShenDepartment of Pharmacy, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing Municipal, P. R. China.
Shudong LiuDepartment of Neurology, The Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing Municipal, P. R. China.ORCID 0000-0002-4592-3744

Funding

Research Project Funding Program of the Affiliated Yongchuan Hospital of Chongqing Medical University, Chongqing Clinical Pharmacy Key Specialties Construction Project YJJL2024085
6 · The paper itself

Abstract

rationaleAcute fluoroacetamide poisoning is a rare and life-threatening emergency. Diagnosis is challenging due to nonspecific symptoms and a latent period. This report emphasizes the effectiveness of delayed acetamide treatment and the importance of neuroimaging for diagnosis and monitoring. PATIENT CONCERNS: A 58-year-old man was admitted to the emergency room about 5 hours after intentionally ingesting an unknown pesticide following a personal conflict. DIAGNOSES: Fluoroacetamide poisoning was initially suspected based on prior domestic case reports, the patient history of pesticide ingestion, clinical signs, and diffusion-weighted magnetic resonance imaging (MRI) showing characteristic features of cytotoxic edema in specific brain regions. Upon confirming the pesticide product with the seller, the diagnosis was ultimately confirmed as fluoroacetamide poisoning.

interventionsGastric lavage, intramuscular acetamide, fluid resuscitation, and electrolyte correction were administered. OUTCOMES: The patient showed rapid clinical improvement after receiving acetamide. He was discharged after one week without any additional medication. Follow-up MRI at one month showed complete resolution of the previous abnormalities, and he reported no symptoms at the one-year follow-up. LESSONS: This case highlights the potential advantages of delaying acetamide treatment and suggests that brain diffusion-weighted MRI could be valuable in diagnosing and monitoring acute fluoroacetamide poisoning.

Indexed as

AcetamidesFluoroacetatesNeuroimagingDiffusion Magnetic Resonance ImagingGastric LavageHumansMaleMiddle AgedacetamideAcetamidesfluoroacetamideFluoroacetatesacetamidefluoroacetamidefluoroacetic acid derivativesmagnetic resonance imagingreversible leukoencephalopathy

Identifiers

PMID42153809
PMCPMC13183027

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.