Evidence map›Paper›PMID 42153735›Full record

ArticleThe Journal of craniofacial surgery2026

Factors Associated With Longitudinal Quality of Life Related to Facial Differences in Youth With Cleft Lip and Palate in Treatment for Class III Malocclusion.

Alexis L Johns, Julia Zukin, Cathrine Fong, Amarjit Dass, Barbara Sheller, Hitesh P Kapadia, Stephen L-K Yen

Abstract read
In one paragraph

Article in The Journal of craniofacial surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Positive Longitudinal Caregiver Behavioral Ratings and Self-Reported Quality of Life in Youth With Cleft Lip and Palate in Treatment for Class III Malocclusion.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexis L JohnsDivision of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California.
Julia ZukinDivision of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California.
Cathrine FongDepartment of Pediatrics, Division of Dentistry, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Amarjit DassDepartment of Pediatrics, Division of Dentistry, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Barbara ShellerDepartment of Dentistry, Seattle Children's Hospital and School of Dentistry, University of Washington, Seattle, WA.
Hitesh P KapadiaDepartment of Dentistry, Seattle Children's Hospital and School of Dentistry, University of Washington, Seattle, WA.
Stephen L-K YenDepartment of Pediatrics, Division of Dentistry, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA.

Funding

CLINICAL EFFECTIVENESS OF LATE MAXILLARY PROTRACTION FOR CLEFT LIP AND PALATEU01DE022937 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YEN, STEPHEN L-K · 2013 to 2017
$3.4M
NIDCR NIH HHS U01 DE022937
6 · The paper itself

Abstract

This prospective longitudinal cohort study described quality of life (QoL) related to facial differences in youth with cleft lip and palate (CLP). Participants completed the Youth Quality of Life-Facial Differences (YQOL-FD) before (n=114) and after (n=95) treatment for class III malocclusion with protraction (58%) or orthognathic surgery (42%). The YQOL-FD has 5 perceptual scales (Positive Consequences, Coping, Negative Consequences, Negative Self-Image, and Stigma), scored 0 to 100 and 18 independent contextual items. Analyses included correlations and t tests for pretreatment to post-treatment and treatment outcome. Participants had a mean age of 14.8±2.9 years pretreatment and 16.9±2.4 post-treatment. They were mostly Latino (68%) males (57%) born with unilateral CLP (76%) with public insurance (62%) and low socioeconomic status (SES; 42%). QoL varied with medium positive scale means (47.6±31.2 to 59.7±23.4 out of 100) and low negative scale means (10.5±14.8 to 25.7±23.8 out of 100). Post-treatment, staring, teasing, being spoken to slowly/loudly, and having to repeat themselves significantly decreased with small effect sizes (Cohen's d = 0.24 to 0.37). While walking in public also decreased post-treatment for the total sample, the only significant change based on successful treatment outcome was increased walking in public. Correlations were small to large (r = -0.19 to 0.66) with both positive and negative associations across Perceptual Scales for medical, sociodemographic, and contextual items, reflecting the complexity of QoL. Completing treatment was associated with modest QoL improvements regardless of treatment outcome. Understanding factors associated with QoL informs screening and interventions for individuals with CLP.

Indexed as

Class III malocclusioncleft lip and palatequality of life

Identifiers

PMID42153735
PMCPMC13300917

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.