Evidence map›Paper›PMID 42153652›Full record

ArticleApplied and environmental microbiology2026

RegB/A-dependent redox regulation links iron uptake to methanol metabolism in

Wooyoung Park, Seungwoo Cha, Hyeonwoo Mun, Kang-Lok Lee, Sang Woo Seo, Ji-Sook Hahn

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wooyoung Park *Department of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.ORCID 0009-0004-8397-1124
Seungwoo Cha *Department of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.ORCID 0009-0003-5941-5817
Hyeonwoo MunDepartment of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.
Kang-Lok LeeDepartment of Biology Education, IALS, Gyeongsang National University, JinJu, Republic of Korea.
Sang Woo SeoDepartment of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0002-7434-7053
Ji-Sook HahnDepartment of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0002-3710-3674

Funding

Korea Health Industry Development Institute HI19C1352National Research Foundation of Korea RS-2024-00335810National Research Foundation of Korea RS-2025-02214910National Research Foundation of Korea RS-2025-02263193
6 · The paper itself

Abstract

Methanotrophs primarily use methane as a carbon and energy source, but they can also grow on methanol. However, methanol assimilation in the absence of methane oxidation results in a redox imbalance due to the accumulation of NADH. In IMPORTANCE: Methanotrophs are emerging as sustainable platforms for converting methane into value-added chemicals. Many species can also utilize methanol-a readily available and industrially attractive alternative-as a carbon source. However, their broader industrial applications have been limited by an incomplete understanding of the fundamental physiological processes that underlie their metabolic and regulatory responses. In this study, we demonstrate how

Indexed as

Bacterial ProteinsIronMethanolMethylomonasGene Expression Regulation, BacterialOxidation-ReductionBacterial ProteinsIronMethanolRegA protein, Bacteriairon uptakemethanol redox stressmethanotrophNa⁺-transporting NADH:ubiquinone reductaseRegB/RegA redox sensor

Identifiers

PMID42153652
PMCPMC13274454

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.