Evidence map›Paper›PMID 42153623›Full record

ArticleeLife2026

Full factorial construction of synthetic microbial communities.

Juan Diaz-Colunga, Pablo Catalan, Magdalena San Roman, Andrea Arrabal, Alvaro Sanchez

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. iScience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juan Diaz-Colunga *Instituto de Biología Funcional y Genómica (IBFG), CSIC and Universidad de Salamanca, Salamanca, Spain.ORCID https://orcid.org/0000-0001-8995-4529
Pablo Catalan *Grupo Interdisciplinar de Sistemas Complejos (GISC), Departamento de Matemáticas, Universidad Carlos III de Madrid, Leganés, Spain.ORCID https://orcid.org/0000-0003-2826-4684
Magdalena San Roman *Instituto de Biología Funcional y Genómica (IBFG), CSIC and Universidad de Salamanca, Salamanca, Spain.ORCID https://orcid.org/0000-0002-2593-7727
Andrea Arrabal *Instituto de Biología Funcional y Genómica (IBFG), CSIC and Universidad de Salamanca, Salamanca, Spain.
Alvaro Sanchez *Instituto de Biología Funcional y Genómica (IBFG), CSIC and Universidad de Salamanca, Salamanca, Spain.ORCID https://orcid.org/0000-0002-2292-5608

Funding

European Research Council 101088469Spanish National Plan for Scientific and Technical Research and Innovation PID2021-125478NAI00Spanish National Plan for Scientific and Technical Research and Innovation PID2022-142185NB-C21Spanish National Plan for Scientific and Technical Research and Innovation PID2022-142185NB-C22
6 · The paper itself

Abstract

Constructing combinatorially complete species assemblages is often necessary to dissect the complexity of microbial interactions and to find optimal microbial consortia. At the moment, this is accomplished through either painstaking, labor-intensive liquid handling procedures, or through the use of state-of-the-art microfluidic devices. Here, we present a simple, rapid, low-cost, and highly accessible liquid handling methodology for assembling all possible combinations of a library of microbial strains, which can be implemented with basic laboratory equipment. To demonstrate the usefulness of this methodology, we construct a combinatorially complete set of consortia from a library of eight

Indexed as

Microbial ConsortiaPseudomonas aeruginosaSynthetic BiologyBiomassMicrobial Interactionscommunity-function landscapeecologymicrobial consortiamicrobial ecologyPseudomonas aeruginosasynthetic microbial communities

Identifiers

PMID42153623
PMCPMC13186563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.