Evidence map›Paper›PMID 42153602›Full record

ArticleExperimental physiology2026

The isolated working guinea pig heart: A functional and electrophysiological characterisation.

Grace C Anderson-Barker, Michael J Shattock

Abstract read
In one paragraph

Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Grace C Anderson-BarkerSchool of Cardiovascular and Metabolic Medicine and Sciences, King's College London, The Rayne Institute, St Thomas' Hospital, London, UK.ORCID https://orcid.org/0000-0001-6374-1445
Michael J ShattockSchool of Cardiovascular and Metabolic Medicine and Sciences, King's College London, The Rayne Institute, St Thomas' Hospital, London, UK.ORCID https://orcid.org/0000-0001-6242-7585

Funding

British Heart Foundation RE/18/2/34213British Heart Foundation RE/24/130035British Heart Foundation RG/12/4/29426
6 · The paper itself

Abstract

Small animal isolated perfused hearts have been used for over 150 years for the study of cardiac physiology and pharmacology. The guinea pig heart represents the smallest mammalian heart that replicates key features of the human heart - for example, with respect to cardiac action potential duration, ion channel expression, excitation-contraction coupling and intracellular Ca

Indexed as

HeartAction PotentialsAnimalsElectrocardiographyExcitation Contraction CouplingGuinea PigsHeart RateIsolated Heart PreparationMyocardial Contractioncontractile functionECGguinea pigIsolated heartLangendorffworking heart

Identifiers

PMID42153602
PMCPMC13327299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.