Review in Channels (Austin, Tex.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors.
Alexander J WinkleFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.ORCID 0000-0003-1226-2449
Aparna Odayil MuralidharanFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Christian Renee McClenneyFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Kamellia KarimpourFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Taukeed Muhammad AshfaqueFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Shaihrum QureshiFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Thomas J HundFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Drew NassalFrick Center for Heart Failure and Arrhythmia, Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA.ORCID 0000-0002-8018-3913
Funding
Distinct Ion Channel Pools and Intercalated Disk Nanoscale Structure Regulate Cardiac ConductionR01HL165751 · NHLBI · OHIO STATE UNIVERSITY · PI Thomas Jeffrey Hund, Rengasayee Veeraraghavan · 2023 to 2026
$2.9M
Role of TREK-1 in modulating cardiac excitability and arrhythmiaR01HL156652 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY · 2021 to 2024
$1.7M
Novel role for the spectrin cytoskeleton in regulation of cardiac fibroblast activity, long-range communication and injury-induced fibrosisR01HL171689 · NHLBI · OHIO STATE UNIVERSITY · PI Thomas Jeffrey Hund · 2024 to 2026
$1.6M
Regulation of STAT3 phosphorylation and its role in orienting myocyte hypertrophyR00HL157684 · NHLBI · OHIO STATE UNIVERSITY · PI Drew Nassal · 2024 to 2026
TREK-1 (KCNK2) is a polymodal two-pore domain potassium (K2P) channel that functions as a background K
Indexed as
Potassium Channels, Tandem Pore DomainAnimalsHumansSignal Transductionpotassium channel protein TREK-1Potassium Channels, Tandem Pore Domainarrhythmiadepressionheart failuretherapeutic targetTREK-1
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Role for TREK-1 as a polymodal sensor and regulator of cell activity. · full record | OpenQuestion