Evidence map›Paper›PMID 42153231›Full record

ArticleJournal of Korean medical science2026

Seroprevalence of Japanese Encephalitis Virus, and Immunogenicity of the Vero-Cell Culture-Derived Vaccine in Hematopoietic Stem Cell Transplantation Recipients.

Haejeong Lee, Ji-Man Kang, Minyoung Kim, Hyojung Park, Bonhyang Na, Younhee Park, Jong Gyun Ahn, Eunyoung Lee, Hyewon Lee, Hyeon Jin Park and 1 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haejeong Lee *Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2087-5077
Ji-Man Kang *Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0678-4964
Minyoung KimDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0070-517X
Hyojung ParkDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0008-2614-1641
Bonhyang NaDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4078-5741
Younhee ParkDivision of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8458-1495
Jong Gyun AhnDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5748-0015
Eunyoung LeeDepartment of Hematology-Oncology, Center for Hematologic Malignancy, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0002-8463-7783
Hyewon LeeDepartment of Hematology-Oncology, Center for Hematologic Malignancy, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-6915-329X
Hyeon Jin ParkCenter for Pediatric Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0002-9557-3412
Hyeon-Seok EomDepartment of Hematology-Oncology, Center for Hematologic Malignancy, National Cancer Center, Goyang, Korea. hseom@ncc.re.kr.ORCID https://orcid.org/0000-0002-0484-2067

Funding

Ministry of EducationMinistry of Health and Welfare HV21C0050010021National Research Foundation of Korea 2019R1A6A1A03032869National Research Foundation of Korea 2021R1I1A1A0104968111Vaccine Innovation Technology Alliance Korea
6 · The paper itself

Abstract

backgroundRevaccination against Japanese encephalitis virus (JEV) in adult hematopoietic stem cell transplantation (HSCT) recipients is not recommended because of insufficient data regarding its efficacy and immunogenicity. Therefore, we aimed to evaluate JEV seropositivity in adult HSCT recipients and explored the seroconversion rate in pediatric HSCT recipients after vaccination against JEV.

methodsThis prospective study was conducted at the National Cancer Center, Goyang, Korea. Adult HSCT recipients (n = 103) were enrolled who visited the outpatient clinic. Additionally, pediatric recipients (< 19 years old; n = 11) who received JEV vaccination were enrolled. We collected serum samples from these participants and healthy healthcare workers (n = 50) for comparison. The JEV seropositivity rates and anti-JEV antibody titers were evaluated using the plaque reduction neutralization test.

resultsThe JEV seropositivity rates were significantly lower in adult HSCT recipients than in healthy healthcare workers (55% vs. 92%,

conclusionThe low anti-JEV antibody seropositivity rate in Korean adult HSCT recipients indicates an increased vulnerability to this virus. Our findings provide a theoretical basis for the potential establishment of appropriate prevention strategies targeting this high-risk group.

Indexed as

Encephalitis, JapaneseEncephalitis Virus, JapaneseHematopoietic Stem Cell TransplantationJapanese Encephalitis VaccinesAdolescentAdultAnimalsAntibodies, ViralChildChild, PreschoolChlorocebus aethiopsFemaleHumansMaleMiddle AgedProspective StudiesAntibodies, ViralJapanese Encephalitis VaccinesHematopoietic Stem Cell TransplantationImmunogenecityJapanese Encephalitis VaccineJapanese Encephalitis VirusSeroprevalance

Identifiers

PMID42153231
PMCPMC13187400

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.