Evidence map›Paper›PMID 42153230›Full record

ArticleJournal of Korean medical science2026

Comparative Network Structures of Hikikomori (Social Withdrawal) Symptoms in Korean and Japanese Psychiatric Patients Prescribed Antidepressants: Findings From the Research on Asian Psychotropic Patterns for Antidepressants, Phase 3.

Eunjae Lee, Eunkyung Kim, Jinwoong Yoon, Kyung Seu Yoon, Tae Young Choi, Seok Woo Moon, Sung-Won Jung, Hyung-Jun Yoon, Hyun Soo Kim, Eunsoo Moon and 14 more

Abstract readComparative Study
In one paragraph

Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Eunjae LeeDepartment of Psychiatry, Hanyang University Guri Hospital, Guri, Korea.ORCID https://orcid.org/0000-0002-3957-0233
Eunkyung KimDepartment of Psychiatry, Hanyang University Guri Hospital, Guri, Korea.ORCID https://orcid.org/0000-0002-7881-2995
Jinwoong YoonDepartment of Psychiatry, Hanyang University Guri Hospital, Guri, Korea.ORCID https://orcid.org/0000-0002-2919-0114
Kyung Seu YoonDepartment of Psychiatry, Hanyang University Guri Hospital, Guri, Korea.ORCID https://orcid.org/0009-0009-9785-9148
Tae Young ChoiDepartment of Psychiatry, Daegu Catholic University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0003-2677-9297
Seok Woo MoonDepartment of Psychiatry and Research Institute of Medical Science, Konkuk University Chungju Hospital, Konkuk University School of Medicine, Chungju, Korea.ORCID https://orcid.org/0000-0002-1074-8122
Sung-Won JungDepartment of Psychiatry, Keimyung University Dongsan Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-2300-742X
Hyung-Jun YoonDepartment of Psychiatry, Chosun University Hospital, Gwangju, Korea.ORCID https://orcid.org/0000-0003-3087-8853
Hyun Soo KimDepartment of Psychiatry, College of Medicine, Dong-A University, Busan, Korea.ORCID https://orcid.org/0000-0003-2171-4400
Eunsoo MoonDepartment of Psychiatry, Pusan National University School of Medicine, Yangsan, Korea.ORCID https://orcid.org/0000-0002-8863-3413
Yangsik KimDepartment of Psychiatry, Inha University Hospital, College of Medicine, Inha University, Incheon, Korea.ORCID https://orcid.org/0000-0003-1841-727X
Hyun-Ju YangDepartment of Psychiatry, Jeju National University College of Medicine, Jeju, Korea.ORCID https://orcid.org/0000-0001-8175-6122
Narae JeongDepartment of Psychology, College of Social Sciences, Daegu University, Gyeongsan, Korea.ORCID https://orcid.org/0000-0003-4407-678X
Ki Won KimWorkplace Mental Health Institute, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7594-0142
Yukako NakagamiStudent Support Center, Kyoto University, Kyoto, Japan.ORCID https://orcid.org/0000-0001-7495-8957
Sota KyuragiDepartment of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0003-0578-3510
Keitaro MatsuoDepartment of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0009-0006-7527-0269
Toshio MatsushimaDepartment of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.ORCID https://orcid.org/0000-0003-0409-6671
Toshiya InadaDepartment of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID https://orcid.org/0000-0002-8427-5639
Shih-Ku LinDepartment of Psychiatry, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0002-5123-0389
Norman SartoriusAssociation for the Improvement of Mental Health Programs, Geneva, Switzerland.ORCID https://orcid.org/0000-0001-8708-6289
Naotaka ShinfukuSchool of Human Sciences, Seinan Gakuin University, Fukuoka, Japan.ORCID https://orcid.org/0000-0002-7390-9077
Takahiro A KatoDepartment of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.ORCID https://orcid.org/0000-0001-5169-2930
Seon-Cheol ParkDepartment of Psychiatry, Hanyang University Guri Hospital, Guri, Korea.ORCID https://orcid.org/0000-0003-3691-4624

Funding

Government of the Republic of KoreaJapan Agency for Medical Research and Development JP21wm0425010Japan Science and Technology Agency JPMJCR22N5Japan Society for the Promotion of Science JP22H00494National Research Foundation of Korea NRF-2024K2A9A08000106
6 · The paper itself

Abstract

backgroundThis study aimed to compare the symptom structures of hikikomori in Korea and Japan through a network analysis approach, addressing the scarcity of comparative research and elucidating potential cross-cultural differences in its manifestation.

methodsData were derived from the Research on Asian Psychotropic Prescription Patterns, Phase 3 (REAP-AD3) study, involving psychiatric patients in Korea and Japan. Social withdrawal symptoms were assessed using the one-month version of the 25-item Hikikomori Questionnaire (HQ-25M). Network analyses were performed to characterize symptom interconnections and centrality in both cohorts. Differences in network structure, edge strength, and global strength were evaluated using the network comparison test (NCT).

resultsThe NCT indicated no statistically significant differences in network structure invariance between Korean and Japanese patients. Notably, the most frequently endorsed symptom among Korean psychiatric patients was "no one to discuss important matters with," whereas for Japanese psychiatric patients it was "difficulty enjoying social situations."

conclusionAlthough overall network structures were largely comparable, the findings suggest subtle distinctions in the organization of social withdrawal symptoms between Korean and Japanese psychiatric patients. These differences underscore the importance of developing culturally tailored preventive and therapeutic strategies for hikikomori in these populations.

Indexed as

Antidepressive AgentsMental DisordersAdultCross-Cultural ComparisonEast Asian PeopleFemaleHumansJapanMaleMiddle AgedRepublic of KoreaSurveys and QuestionnairesAntidepressive AgentsHikikomoriJapanKoreaNetwork AnalysisOne-Month 25-Item Hikikomori Questionnaire (HQ-25M)Social Withdrawal

Identifiers

PMID42153230
PMCPMC13187401

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.