Evidence map›Paper›PMID 42153173›Full record

ArticleAnnals of clinical epidemiology2026

Community pharmacist-led educational intervention to recommend ophthalmology visits for patients with diabetes: a cluster randomized controlled trial.

Ai Ogawa, Shinji Okabayashi, Tatsuhiko Suzuki, Hiroshi Sudo, Yosuke Yamamoto

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Article in Annals of clinical epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Ai OgawaTotal Medical Service Co., Ltd., Fukuoka, Japan.
Shinji OkabayashiDepartment of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Tatsuhiko SuzukiMedical System Network Co., Ltd., Tokyo, Japan.
Hiroshi SudoNanohana Pharmacy Mitoekimaeten, Ibaraki, Japan.
Yosuke YamamotoDepartment of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt remains unclear whether pharmacist-led educational programs in community pharmacies could increase appropriate ophthalmic visits for patients with diabetes. We assessed efficacy of pharmacist-led education on ophthalmology visits for diabetes.

methodsWe conducted a cluster randomized controlled trial at 32 community pharmacies in Japan, targeting individuals with diabetes with no ophthalmic visits over a year. Pharmacists in the intervention group received online training on diabetic retinopathy and educated patients, while the control group received a pamphlet. The primary outcome was ophthalmic visits during the follow-up period. Generalized estimating equations were performed with two adjusted models: age and sex (model 1), and additionally diabetic retinopathy factors (model 2). Key secondary outcomes were changes in behavior for ophthalmic visits and glycated hemoglobin (HbA1c) levels.

resultsOverall, 268 patients were included (133 intervention and 135 control). Participants' mean age was 60.1 years, and HbA1c level was 7.5%. Ophthalmic visits occurred in 18.8% (25/133) of the intervention and 20.7% (28/135) of the control group, yielding no significant difference (model 1, risk difference [RD] -0.03 [-0.14 to 0.08], risk ratio [RR] 0.88 (0.54 to 1.45); model 2, RD -0.07 [-0.21 to 0.08], RR 0.73 [0.41 to 1.30]). There was no significant difference between the two groups in the mean changes from baseline to 6 months in behavior for ophthalmic visits (0.07 [-0.23 to 0.37]) and HbA1c levels (-0.28 [-0.76 to 0.20]).

conclusionsPharmacist-led education on diabetic retinopathy did not increase ophthalmology visits or improve diabetes-related outcomes. Effective strategies to encourage ophthalmology visits are required.

Indexed as

diabetes mellitusdiabetic retinopathypamphletpharmaciespharmacists

Identifiers

PMID42153173
PMCPMC13180486

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