Evidence map›Paper›PMID 42153163›Full record

ArticleThe Pan African medical journal2026

Extracapillary immunoglobulin A nephropathy glomerulonephritis discovered during the course of pulmonary tuberculosis: a case report.

Asma Bettaieb, Raja Aoudia, Meriam Khadhar, Sarra Hadded, Hanene Gaied, Ines Moussa, Leila Douik El Gharbi, Mouna Jerbi, Rym Goucha

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In one paragraph

Article in The Pan African medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Asma BettaiebDepartment of Nephrology, Mongi Slim Hospital, Tunis, Tunisia.
Raja AoudiaDepartment of Nephrology, Mongi Slim Hospital, Tunis, Tunisia.
Meriam KhadharDepartment of Nephrology, Mongi Slim Hospital, Tunis, Tunisia.
Sarra HaddedDepartment of Nephrology, Mongi Slim Hospital, Tunis, Tunisia.
Hanene GaiedDepartment of Nephrology, Mongi Slim Hospital, Tunis, Tunisia.
Ines MoussaFaculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.
Leila Douik El GharbiFaculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.
Mouna JerbiDepartment of Nephrology, Mongi Slim Hospital, Tunis, Tunisia.
Rym GouchaDepartment of Nephrology, Mongi Slim Hospital, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few cases of immunoglobulin A nephropathy (IgAN) associated with tuberculosis have been described in the literature. We report an atypical case of extracapillary IgA glomerulonephritis discovered during the course of pulmonary tuberculosis. The patient, a 45-year-old diagnosed with pulmonary tuberculosis, presented with mixed nephrotic syndrome, characterized by hypertension, hematuria, and acute renal failure. We completed a renal biopsy which showed IgAN with diffuse crescents, classified as (M1E1S1T0C2) according to the Oxford classification. The patient was treated with high-dose of intravenous corticosteroids followed by oral tapering. The antituberculous quadruple therapy was extended to 2.5 months then followed by dual therapy. The course was marked by recovery from pulmonary tuberculosis and a significant improvement in creatinine levels, from 504 µmol/l to 262 µmol/L in five months, but the nephrotic syndrome persisted. In the absence of specific guidelines, this case demonstrates that individualized corticosteroid therapy may be considered in extracapillary IgA glomerulonephritis associated with tuberculosis.

Indexed as

Antitubercular AgentsGlomerulonephritis, IGATuberculosis, PulmonaryAcute Kidney InjuryAdrenal Cortex HormonesBiopsyCreatinineHumansMaleMiddle AgedNephrotic SyndromeAdrenal Cortex HormonesAntitubercular AgentsCreatininecase reportcrescentic glomerulonephritisimmunoglobulin A nephropathyrenal failuretuberculosis

Identifiers

PMID42153163
PMCPMC13179870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.