ArticleCureus2026
A Case of TAFRO (Thrombocytopenia, Anasarca, Fever or Fibrosis of the Bone Marrow, Renal Dysfunction, and Organomegaly): Exploring the Idiopathic Variant of Multicentric Castleman Disease.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Characterized by Thrombocytopenia, Anasarca, Fever or Fibrosis of the bone marrow, Renal dysfunction, and Organomegaly, TAFRO syndrome is a rare systemic inflammatory disorder often presenting with diffuse lymphadenopathy and characteristic lymph node histopathology. Given its rapid progression and overlapping presentation with other systemic diseases, early diagnosis and treatment are vital for improving patient outcomes. Here, we report the case of a 43-year-old male with a medical history of chronic kidney disease and heart failure who presented with progressive anasarca and respiratory distress. The composite of clinical, laboratory, and histopathologic findings met the diagnostic criteria for TAFRO syndrome. The patient was treated with high-dose corticosteroids and anti-interleukin-6 therapy, leading to improvement of his symptoms. This case underscores the importance of integrating clinical features with histopathologic findings for early recognition and prompt initiation of immunosuppressive and anti-cytokine therapy to optimize the clinical outcomes of patients with TAFRO syndrome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.