Evidence map›Paper›PMID 42152986›Full record

ArticleJRSM open2026

Effect of COVID-19 NHS breast screening pause on breast cancer presentation and management: an insight into overdiagnosis.

Rachel Aquilina, Jajini Varghese, Jayant S Vaidya, Uma J Vaidya

Abstract read
In one paragraph

Article in JRSM open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rachel AquilinaUniversity College London, London, UK.ORCID https://orcid.org/0009-0007-6658-7966
Jajini VargheseDivision of Surgery and Interventional Science, University College London, London, UK.ORCID https://orcid.org/0000-0001-8189-5608
Jayant S VaidyaDivision of Surgery and Interventional Science, University College London, London, UK.ORCID https://orcid.org/0000-0003-1760-1278
Uma J VaidyaImperial College Healthcare NHS Trust, London, UK.ORCID https://orcid.org/0000-0002-8121-7863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To ascertain the impact of a 3-month pause in the NHS Breast Screening Programme (NHSBSP) during COVID-19 on numbers, characteristics and outcomes of breast cancer patients. Design: We compared numbers, referral sources (NHSBSP/GP), tumour characteristics, treatments, and survival before and during COVID-19 using chi-square tests and Kaplan-Meier estimates. Patients were grouped into: (a) all cases from 2019 to 2021 ( Setting: The study was conducted with the breast units of two large London NHS hospitals as a local audit to understand the impact of COVID-19 on breast cancer management. Participants: Patients diagnosed with breast cancer from 2019 to 2021 were analysed. Main outcome measures: Temporal variation in the number of breast cancer cases by referral source and the impact of the pause in screening mammography due to the COVID-19 pandemic on changes in tumour characteristics, treatments and survival. Results: Overall, there were 31% fewer patients in 2020 vs. 2019 (886 vs. 1281, Conclusions: During the COVID-19-induced NHSBSP pause, good-prognosis (grade 1) cancers reduced without an increase in larger, or node-positive cancers, or more extensive surgery, and 3-year survival remained unchanged, suggesting that pausing NHSBSP may have avoided overdiagnosis without causing harm.

Indexed as

Barnet and chase farm hospitalsBreast cancerCOVID-19national health service breast screening programmepandemicroyal free hospitalscreening

Identifiers

PMID42152986
PMCPMC13180073

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.