ArticleJournal of inflammation research2026
Predictive Value of Uric Acid-to-Albumin Ratio for Left Atrial Thrombus or Spontaneous Echo Contrast in Patients with Non-Valvular Atrial Fibrillation.
Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The uric acid-to-albumin ratio (UAR) is a novel inflammatory marker linked to cardiovascular disease. This study aimed to evaluate the predictive value of UAR for left atrial thrombus or spontaneous echo contrast (LAT/SEC) in non-valvular atrial fibrillation (NVAF), explore its mediating mechanisms, and assess the incremental value beyond the CHA Methods: This retrospective study included 514 patients with NVAF undergoing transesophageal echocardiography (TEE). Multivariable logistic regression, restricted cubic splines (RCS), generalized additive models (GAMs), receiver operating characteristic (ROC) curves, and mediation analyses were employed to evaluate the relationship between UAR and LAT/SEC. Reclassification indices assessed UAR's incremental value beyond the CHA Results: The prevalence of LAT/SEC was 17.32%. UAR was independently associated with LAT/SEC (OR: 1.43, 95% CI: 1.25-1.66; Conclusion: UAR is an independent predictor of LAT/SEC in patients with NVAF, outperforming its individual components and providing significant incremental value beyond the CHA
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