Evidence map›Paper›PMID 42152727›Full record

ReviewClinical and translational medicine2026

Quantum biology: From mechanisms to medicine.

Ji-Yong Sung, Jae-Ho Cheong

Abstract readReview
In one paragraph

Review in Clinical and translational medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ji-Yong SungDepartment of Neurosurgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Republic of Korea.
Jae-Ho CheongInstitute for Convergence Research and Education in Advanced Technology, Yonsei University, Seoul, Republic of Korea.

Funding

Korean ARPA-H Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea RS-2025-25456722"Regional Innovation System & Education (RISE)" through the Seoul RISE Center, funded by the Ministry of Education (MOE) and the Seoul Metropolitan Government. 2025-RISE-01-022-05
6 · The paper itself

Abstract

backgroundQuantum biology explores how quantum mechanical phenomena-including coherence, tunneling, superposition, and spin dynamics-contribute to biological function. Although once considered negligible in warm and noisy biological environments, increasing evidence suggests that quantum effects play important roles in diverse living systems.

objectiveThis review aims to summarize the current understanding of quantum biological mechanisms, highlight their relevance to physiology and disease, and discuss emerging biomedical and technological applications.

methodsWe reviewed recent experimental, computational, and theoretical advances in quantum biology, including studies employing ultrafast spectroscopy, quantum sensing, cryo-electron microscopy, and quantum simulation approaches. Key biological systems examined include photosynthetic complexes, enzymatic reactions, DNA base pairing, sensory systems, and mitochondrial electron transport.

resultsAccumulating evidence indicates that quantum coherence, tunneling, and spin-dependent processes contribute to photosynthetic energy transfer, enzymatic catalysis, proton transfer in DNA, magnetoreception, olfaction, and mitochondrial bioenergetics. Advances in quantum sensing and computational modeling have further enabled direct investigation of coherence dynamics and electron transfer mechanisms in biological systems. These findings suggest that quantum effects may influence aging, cancer, neurodegeneration, and metabolic dysfunction through mechanisms involving reactive oxygen species production, mutagenesis, and altered redox signaling.

conclusionQuantum biology is evolving from a speculative concept into an experimentally accessible and translationally relevant discipline. Integrating quantum principles with systems biology, multi-omics, and precision medicine may provide new opportunities for diagnostics, biomarker discovery, and therapeutic development. Continued advances in spectroscopy, quantum sensing, and quantum computing are expected to further establish the role of quantum phenomena in health and disease.

Indexed as

BiologyQuantum TheoryDNA proton tautomerisation and mutationmitochondrial electron transport and ROSquantum biologyquantum coherence and tunnellingquantum‐informed medicineradical pair mechanismspin dynamics

Identifiers

PMID42152727
PMCPMC13184552

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.