ReviewJournal of cosmetic dermatology2026
Mechanically Induced Skin Renewal: Evidence-Based Insights Into Clinical, Structural and Inflammatory Changes Activated by Microneedling, Microdermabrasion and Microvibration.
Review in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
backgroundDevice-based aesthetic procedures such as microneedling, microdermabrasion and microvibration have gained widespread clinical and institutional use for skin rejuvenation, yet the underlying biological mechanisms and the robustness of clinical evidence remain incompletely established.
objectiveThis review synthesizes current clinical, histological and molecular data to evaluate the efficacy, safety and mechanistic pathways engaged by these instrument-assisted dermatologic interventions.
methodsA comprehensive literature search of clinical trials, in vivo and ex vivo analyses, and mechanistic studies was conducted to examine outcomes related to clinical skin appearance, inflammatory signaling and protein expression.
resultsThis review summarizes clinical, histological, and molecular evidence on these interventions. All modalities influence skin texture, scarring, and epidermal renewal, primarily through transient activation of inflammatory pathways, followed by fibroblast activation and extracellular matrix remodeling. Understanding these pathways can guide treatment selection and optimization, while standardized studies and deeper proteomic analyses are needed to refine personalized approaches.
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Registered trials
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