Evidence map›Paper›PMID 42152584›Full record

ArticleJournal of medical virology2026

Prevalence and Risk Factors for Persistent Post-COVID-19 Condition at 3, 6, 12, and 18 Months After Initial Infection Among Adults Living in a Community of Japan: Yao COVID-19 Study.

Miyuki Hori, Mina Hayama-Terada, Akihiko Kitamura, Mariko Hosozawa, Yoko Muto, Arisa Iba, Yoshihiro Takayama, Takashi Kimura, Hiroyasu Iso

Abstract read
In one paragraph

Article in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miyuki HoriInstitute for Global Health Policy Research, Bureau of Global Health Cooperation, Japan Institute for Health Security, Tokyo, Shinjuku-ku, Japan.ORCID https://orcid.org/0000-0003-4796-1805
Mina Hayama-TeradaYao City Public Health Center, Osaka, Yao, Japan.
Akihiko KitamuraYao City Public Health Center, Osaka, Yao, Japan.
Mariko HosozawaInstitute for Global Health Policy Research, Bureau of Global Health Cooperation, Japan Institute for Health Security, Tokyo, Shinjuku-ku, Japan.ORCID https://orcid.org/0000-0001-6886-5156
Yoko MutoInstitute for Global Health Policy Research, Bureau of Global Health Cooperation, Japan Institute for Health Security, Tokyo, Shinjuku-ku, Japan.ORCID https://orcid.org/0009-0005-6358-0801
Arisa IbaInstitute for Global Health Policy Research, Bureau of Global Health Cooperation, Japan Institute for Health Security, Tokyo, Shinjuku-ku, Japan.
Yoshihiro TakayamaYao City Public Health Center, Osaka, Yao, Japan.
Takashi KimuraHealth and Environmental Risk Division, National Institute for Environmental Studies, Ibaraki, Japan.
Hiroyasu IsoInstitute for Global Health Policy Research, Bureau of Global Health Cooperation, Japan Institute for Health Security, Tokyo, Shinjuku-ku, Japan.

Funding

MHLW Research on Emerging and Re-Emerging Infectious Diseases and Immunization JPMH21HA2011MHLW Research on Emerging and Re-Emerging Infectious Diseases and Immunization JPMH23HA2011MHLW Research on Emerging and Re-Emerging Infectious Diseases and Immunization JPMH24HA2015MHLW Research on Emerging and Re-Emerging Infectious Diseases and Immunization JPMH25HA2005
6 · The paper itself

Abstract

The risk factors for long-term persistent post-coronavirus disease (COVID-19) condition (PCC) years after infection remain unclear. In this study, we investigated the prevalence of PCC and the associated risk factors after severe acute respiratory syndrome coronavirus 2 infection in the general population. This prospective cohort study included individuals aged 18-79 years diagnosed with COVID-19 between March 2021 and April 2022 and matched non-infected individuals living in Yao City, Japan. Baseline and follow-up surveys were conducted in 2022 and 2024, respectively. PCC was defined as symptoms persisting for ≥2 months at 3 months post-infection. Among 7404 eligible individuals, 3628 (2314 infected, mean age: 44.2 years, 62.7% females; 1314 non-infected, mean age: 45.0 years, 63.2% females) participated in the follow-up survey. PCC prevalence at 3, 6, 12, and 18 months was 14.3%, 12.0%, 6.3%, and 5.4%, respectively. Older age, being overweight, comorbidities, severe disease in the acute phase, and low household income were associated with persistent PCC at ≥ 18 months. Compared with no vaccination, ≥ 2 doses of the COVID-19 vaccine prior to infection were associated with a lower PCC risk. These findings highlight PCC as an important public health concern in the post-COVID-19 era. Trial Registration: UMIN000049807.

Indexed as

COVID-19AdolescentAdultAgedComorbidityFemaleFollow-Up StudiesHumansJapanMaleMiddle AgedPost-Acute COVID-19 SyndromePrevalenceProspective StudiesRisk FactorsSARS-CoV-2COVID‐19Japanlong‐COVIDpost‐COVID‐19 conditionSARS‐CoV‐2

Identifiers

PMID42152584
PMCPMC13184574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.