Evidence map›Paper›PMID 42152130›Full record

Trial reportTrials2026

The 1-year obesity treatment intervention can improve fasting plasma glucose in children aged 6-12 years: randomized controlled trial.

A Martikainen, A M Eloranta, U Schwab, T Örmälä

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06126679 (Effectiveness and Cost Effectiveness of a 1-year Dietary and Physical Activity Intervention of Childhood Obesity - Study Protocol for a Randomized Controlled Clinical Trial), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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NCT06126679 naunknown statusnot on this map

Effectiveness and Cost Effectiveness of a 1-year Dietary and Physical Activity Intervention of Childhood Obesity - Study Protocol for a Randomized Controlled Clinical Trial

TypeinterventionalSponsorHelsinki University Central HospitalRan2019 to 2024Enrolled80ConditionsChildhood ObesityArms1-year dietary and physical activity intervention of childhood obesity
3 · Its place in the literature

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A MartikainenClinical Nutrition, Internal Medicine and Rehabilitation, Helsinki University Hospital, Nonoperative Services, Hyvinkää Hospital, Sairaalankatu 1, 05850, Hyvinkää, Finland. anni.martikainen@hus.fi.ORCID http://orcid.org/0009-0009-6659-5290
A M ElorantaInstitute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.
U SchwabInstitute of Public Health and Clinical Nutrition, School of Medicine, University of Eastern Finland, Kuopio, Finland.
T ÖrmäläPediatric Gastroenterology, MD, Hyvinkää Hospital, Hyvinkää, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLifestyle interventions can reduce the risk of becoming an overweight adult and reduce the risk of health problems. The aim was to investigate the effects of obesity treatment on BMI-for-age, metabolic markers, and quality of life in children with overweight or obesity.

methodsA randomized 1-year lifestyle intervention, including appointments every 3 months, a total of 5 sessions. A multidisciplinary team consisting of a pediatrician, a nurse, and a clinical nutritionist conducted the study. The participants were 6-12-year-old children with overweight or obesity in the Hyvinkää area, Finland. The inclusion criteria were weight for height at least + 40% or ≥ 30% and ascending growth curve. Participants were randomized to the intervention group (n = 21) or the control group (n = 19). The intervention group received lifestyle counseling with an emphasis on nutritional guidance. The control group continued in the primary care and did not have any intervention during the study period. Laboratory values and anthropometric measurements were measured at baseline and at 12 months. In addition, quality of life was evaluated by a questionnaire.

resultsIn the intervention group fasting plasma glucose decreased statistically significantly (p = 0.017) and the difference in the change between the groups approached statistical significance (p = 0.080). No other significant changes were found between the intervention and the control groups at the end of the intervention. The increase of BMI-for-age stopped in both groups.

conclusionEncouragement to healthy lifestyle can improve glucose metabolism in children with obesity and to stop excessive weight gain.

trial registration18.12.2018 (§142/2018, HUS/2666/2018). CLINICALTRIALS: gov Identifier: NCT06126679.

Indexed as

Blood GlucoseFastingPediatric ObesityRisk Reduction BehaviorAge FactorsBiomarkersBody Mass IndexChildCounselingFemaleFinlandHumansMaleQuality of LifeTime FactorsTreatment OutcomeBiomarkersBlood GlucoseChildrenLifestyle interventionMetabolic outcomesOverweight

Identifiers

PMID42152130
PMCPMC13352937

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.