Evidence map›Paper›PMID 42152123›Full record

ArticleBMC research notes2026

Diagnostic accuracy of intraoperative haptoglobin point-of-care testing in ovarian tumor fluid versus frozen section for epithelial ovarian cancer.

Benyamin Rakhmatsyah Titaley, Siti Salima, Andi Kurniadi, Dodi Suardi, Ali Budi Harsono, Gatot Nyarumenteng Adhipurnawan Winarno, Patiyus Agustiansyah, Aisyah Shofiatun Nisa

Abstract read
In one paragraph

Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benyamin Rakhmatsyah TitaleyDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur 38 Bandung, Bandung, West Java, Indonesia. benyamin.rakhmatsyah@gmail.com.
Siti SalimaDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur 38 Bandung, Bandung, West Java, Indonesia.
Andi KurniadiDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur 38 Bandung, Bandung, West Java, Indonesia.
Dodi SuardiDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur 38 Bandung, Bandung, West Java, Indonesia.
Ali Budi HarsonoDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur 38 Bandung, Bandung, West Java, Indonesia.
Gatot Nyarumenteng Adhipurnawan WinarnoDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur 38 Bandung, Bandung, West Java, Indonesia.
Patiyus AgustiansyahDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia.
Aisyah Shofiatun NisaDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Jl. Pasteur 38 Bandung, Bandung, West Java, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOvarian cancer is the third most common gynaecological cancer and has the high mortality rates and requires accurate intraoperative. Haptoglobin is an acute-phase protein locally elevated in cancer cells, may serve as a novel diagnostic marker. This study aimed to evaluate the diagnostic accuracy of a haptoglobin point-of-care test using intraoperatively aspirated ovarian cyst fluid for detecting epithelial ovarian carcinoma.

resultA total of 55 patients with suspected malignant ovarian tumors were enrolled, with 11 excluded, resulting in 44 patients for analysis. Frozen sections were found to have a diagnostic accuracy of 100% compared with histopathology, whereas haptoglobin had an accuracy of 90.91%. The sensitivity, specificity, PPV, and NPV of the haptoglobin test were 90.48, 91.3, 90.49, and 91.3%, respectively. Haptoglobin testing in ovarian cyst fluid demonstrates promising diagnostic performance and may serve as a complementary tool alongside established intraoperative methods.

Indexed as

Carcinoma, Ovarian EpithelialCyst FluidFrozen SectionsHaptoglobinsOvarian NeoplasmsPoint-of-Care TestingAdultAgedBiomarkers, TumorFemaleHumansIntraoperative PeriodMiddle AgedSensitivity and SpecificityBiomarkers, TumorHaptoglobinsDiagnosisEpithelial ovarian cancerFrozen sectionHaptoglobin

Identifiers

PMID42152123
PMCPMC13352984

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.