Evidence map›Paper›PMID 42152112›Full record

ArticleJournal of cardiothoracic surgery2026

Use of argatroban as anticoagulation for cardiopulmonary bypass during heart transplantation: A case report.

Marika Faggioli, Daniela Bacich, Chiara Tessari, Fabio Zanella, Demetrio Pittarello, Annalisa Angelini, Augusto D'Onofrio, Vincenzo Tarzia, Gerosa Gino

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marika FaggioliDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.
Daniela BacichDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.
Chiara TessariDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy. chiara.tessari@unipd.it.
Fabio ZanellaDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.
Demetrio PittarelloDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.
Annalisa AngeliniDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.
Augusto D'OnofrioCardiac Surgery Unit, University of Rome Tor Vergata, Via Cracovia 50, Rome, 00133, Italy.
Vincenzo TarziaDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.
Gerosa GinoDepartment of Cardio Thoracic and Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, Padua, 35128, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeparin-induced thrombocytopenia rules out the possibility of adopting heparin for cardiopulmonary bypass. To overcome this problem two anticoagulants can be used: argatroban and bivalirudin. CASE PRESENTATION: We report on the adoption of argatroban during cardiopulmonary bypass for heart transplantation in a patient affected by HIT, previously implanted with a left ventricular assist device. Despite appropriate dosing, anticoagulation reversal proved ineffective, resulting in uncontrollable coagulopathy and fatal haemorrhage.

conclusionsArgatroban could be an effective option for selected patients but more studies and particular attention are required, especially in patients with previous left ventricular assist device implantation.

Indexed as

AnticoagulantsCardiopulmonary BypassHeart TransplantationPipecolic AcidsAdultAntithrombinsArginineFatal OutcomeHeparinHumansMaleSulfonamidesThrombocytopeniaAnticoagulantsAntithrombinsargatrobanArginineHeparinPipecolic AcidsSulfonamidesArgatrobanBivalirudinHaemorrhageHeart transplantationHeparin induced thrombocytopenia.

Identifiers

PMID42152112
PMCPMC13371257

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.