Evidence map›Paper›PMID 42151963›Full record

Observational studyBMC urology2026

Culture-detected urinary bacteria 10-20 years after tension-free vaginal tape surgery and associations with incontinence, pelvic pain, and dissatisfaction: a cross-sectional study.

Ingrid Volløyhaug, Berit R Solhaug, Kjersti W Larssen, Kjersti Haugum, Maria Ø Nyhus, Rune Svenningsen, Jan E Afset

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMC urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04912830 (Tension Free Vaginal Tape Surgery - Follow up After 10 and 20 Years), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04912830 completednot on this map

Tension Free Vaginal Tape Surgery - Follow up After 10 and 20 Years: Success Rate and Long-term Complications

TypeobservationalSponsorNorwegian University of Science and TechnologyRan2021 to 2023Enrolled1,210ConditionsUrinary Incontinence,StressArmsTension-free vaginal tape
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ingrid VolløyhaugDepartment of Obstetrics and Gynecology, St. Olavs Hospital HF, Trondheim University Hospital , Postboks 3250, Torgarden, Trondheim, N-7006, Norway. ingrid.volloyhaug@ntnu.no.
Berit R SolhaugDepartment of Obstetrics and Gynecology, St. Olavs Hospital HF, Trondheim University Hospital , Postboks 3250, Torgarden, Trondheim, N-7006, Norway.
Kjersti W LarssenDepartment of Medical Microbiology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Kjersti HaugumDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Maria Ø NyhusDepartment of Obstetrics and Gynecology, St. Olavs Hospital HF, Trondheim University Hospital , Postboks 3250, Torgarden, Trondheim, N-7006, Norway.
Rune SvenningsenFaculty of Medicine, University of Oslo, Oslo, Norway.
Jan E AfsetDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSome women have persistent incontinence or pain after tension-free vaginal tape (TVT) surgery. Our objective was to study any association between culture-detected bacteriuria and incontinence, complications and satisfaction 10-20 years after TVT.

methodsCross-sectional study in 2022 of 127 women operated with TVT between 2001-2012 at Trondheim University Hospital, Norway. Validated questionnaires assessed stress urinary incontinence (SUI), urgency urinary incontinence (UUI), pelvic pain and satisfaction. Urine collected by sterile catheterization was cultivated for two (chromogenic and blood agar) and five days (blood, fastidious and chocolate agar). Symptoms and demographics were compared between women with and without significant bacterial growth, defined as ≥ 1.000 CFU/ml for this study, using chi-square test, Fishers exact test, t-test and logistic regression. Number of species detected after five days culture was tested in association to demographics and symptoms using Mann Whitney-U-test.

results50/111 women (45.0%) had SUI, 54/122 (44.3%) had UUI, 95/116 (81.9%) were satisfied and 7/123 (5.7%) stated persistent pain. 16 (12.4%) had significant bacterial growth after two days of whom seven (44%) had a positive dipstick screening test (leukocytes or nitrite). After five days culture, 28 (22%) had significant bacterial growth. We found non-significantly higher odds for SUI (aOR 4.2, 95% CI 0.5-36.1) and UUI (aOR 2.1, 95% CI 0.3-13.7) in women with bacterial growth after two days. Bacterial growth after five days was associated with non-significantly increased risk of SUI (aOR 2.3, 95% CI 0.6-8.9) and UUI (aOR 3.4, 95% CI 0.9-13.6). Age was significantly associated with bacterial growth after two (aOR 1.2, 95% CI 1.02-1.3) and five days (aOR 1.1, 95% CI 1.04-1.2). The number of bacterial species after five days culture was higher in women with UUI, BMI > 75 percentile, in those dissatisfied or with persistent pain, than in women without these conditions (p < 0.01).

conclusionsSignificant bacteriuria and larger variety of bacterial species were associated with incontinence, pain and dissatisfaction 10-20 years after TVT. The dipstick screening test had a sensitivity of only 44%. Extended urinary culture may be of value in optimizing treatment of urinary tract symptoms after TVT.

trial registrationClinicalTrials.gov (NCT04912830).

Indexed as

BacteriuriaPatient SatisfactionPelvic PainPostoperative ComplicationsSuburethral SlingsUrinary Incontinence, StressAgedCross-Sectional StudiesFemaleHumansMiddle AgedTime FactorsPelvic painStress urinary incontinenceTension free vaginal tapeUrgency urinary incontinenceUrinary microbiota

Identifiers

PMID42151963
PMCPMC13371224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.