Evidence map›Paper›PMID 42151897›Full record

ArticleBMC musculoskeletal disorders2026

One in six admitted patients with low back pain received high daily opioid dosage in Australian hospitals: a cross-sectional study.

Qiuzhe Chen, Christina Abdel Shaheed, Chung-Wei Christine Lin, Chris G Maher, Gustavo C Machado

Abstract readMulticenter Study
In one paragraph

Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Qiuzhe ChenSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. qiuzhe.chen@sydney.edu.au.ORCID http://orcid.org/0000-0001-5651-6717
Christina Abdel ShaheedSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Chung-Wei Christine LinSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Chris G MaherSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Gustavo C MachadoSchool of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the amount of opioids administered to patients with low back pain in the hospital setting and to determine factors associated with high daily dosage.

methodsThis cross-sectional study analysed medical records of three public hospitals in Sydney, NSW, Australia. We included adult patients who presented to the emergency department (ED) from January 2016 to October 2021 with non-specific low back pain or radiculopathy. The opioid dose administered in the ED and the daily dosage during hospital stay (if admitted) were estimated using opioid orders measured by milligram of morphine equivalents (MME). High-dose opioid therapy was defined as ≥ 50 MME/day during hospital stay.

resultsOf the 9,345 eligible ED encounters, we included 12,850 opioid orders placed for 5,132 patients (54.9%). Among the 7,633 patients discharged home from ED, 3,519 patients (46.1%) were administered opioids in the ED at an average dose of 13.9 MME (SD = 35.6). 94.2% of patients who were admitted to hospitals (1,613 out of 1,712) received a mean dosage of 34.7 MME/day (SD = 68.3), including 154 patients (9.0%) received 50-90 MME/day and 117 (6.8%) received ≥ 90 MME/day. High-dose opioid therapy was associated with younger age (aOR = 0.80, 95% CI 0.74-0.85), male gender (aOR = 1.38, 95% CI 1.05-1.81), disadvantaged socio-economic status (aOR = 1.50, 95% CI 1.07-2.10), and serious pathology diagnosed during hospital admission (aOR = 1.79, 95% CI 1.36-2.37).

conclusionAlmost one in six admitted patients with low back pain receive a high daily opioid dosage in Australian hospitals. Strategies implementing evidence-based non-opioid alternatives to reduce high-dose opioid therapy are warranted.

Indexed as

Analgesics, OpioidLow Back PainAdultAgedAustraliaCross-Sectional StudiesEmergency Room VisitsEmergency Service, HospitalFemaleHospitalizationHospitals, PublicHumansMaleMiddle AgedNew South WalesAnalgesics, OpioidEmergency departmentHealthcare quality improvementHospital medicineMedication safetyPain

Identifiers

PMID42151897
PMCPMC13393623

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.