SynthesisReproductive sciences (Thousand Oaks, Calif.)2026
An Updated Understanding of Human Embryonic Fragmentation.
Synthesis in Reproductive sciences (Thousand Oaks, Calif.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Metals/Metalloids Profile in Seminal Plasma/Serum of Patients with Asthenozoospermia/Oligozoospermia: Correlation with Semen Quality.Biological trace element research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Embryo fragmentation is a frequent occurrence in human in vitro fertilization (IVF) and has long been associated with diminished embryonic developmental potential and poorer clinical outcomes. Fragmentation, typically observed during early cleavage stages, is triggered by multifactorial influences such as oxidative stress, chromosomal instability, and compromised gamete quality. Although traditionally viewed as a marker of poor prognosis, emerging evidence indicates that mildly fragmented embryos can retain implantation potential depending on the degree and distribution of cytoplasmic fragments. This systematic review summarizes recent advances in the understanding of embryo fragmentation, emphasizing the timing, molecular mechanisms, influencing factors, and clinical relevance. Particular attention is given to the controversies surrounding fragment removal and the prospects for improving embryo assessment in clinical embryology.
Indexed as
Identifiers
42151706What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.