ArticleAesthetic plastic surgery2026
Italian Translation, Cultural Adaptation and Clinical Application of the ACNE-Q: Patient-Reported Outcome Measure in Mild-to-Moderate Facial Acne.
Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionAcne vulgaris (AV) is one of the most common dermatological conditions, affecting over 85% of adolescents and a wide range of young adults. Beyond its cosmetic impact, acne can cause significant psychological and quality of life (QoL) issues, highlighting the importance of patient-reported outcome measures (PROMs). The primary aim of this study was to translate, culturally adapt, and validate the Italian version of the ACNE-Q questionnaire, a disease-specific PROM for acne. The secondary aim was to evaluate the effectiveness of the ACNE-FREE protocol in patients with mild-to-moderate facial acne, using the validated Italian ACNE-Q.
methodsThis prospective study involved 54 patients with mild-to-moderate facial acne treated with the ACNE-FREE protocol. The Italian translation and validation of ACNE-Q followed a rigorous process of forward translation, back-translation, review and patient interviews. Patients completed the ACNE-Q at baseline (T0), after 3 months (T1), and after 6 months (T2). Outcome changes were analyzed with ANOVA test (Prism software).
resultsThe mean age of participants was 25.04 ± 4.23 years, with 39 females and 11 males. All ACNE-Q scale scores demonstrated significant improvements over time, showing reductions in "Symptoms" and "Appearance-related distress" scores (p<0.05), indicating a decrease in symptoms and psychological impact. The "Facial Skin" scale showed an increase in scores, suggestive of clinical improvement. The data support the efficacy of the ACNE-FREE protocol in improving both clinical outcomes and patient QoL.
conclusionsThe ACNE-Q is a reliable and valid tool for assessing patient-reported outcomes in Italian-speaking populations with acne. The ACNE-FREE treatment protocol yielded significant improvements in skin condition and psychosocial parameters, enhancing overall quality of life. An integrated approach addressing both physical symptoms and psychological well-being is essential for optimal acne management. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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