ArticleEye (London, England)2026
Choroidal vascularity profiles in diabetic macular oedema subtypes: a swept-source OCT angiography study.
Article in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo characterise choroidal microvascular changes in diabetic macular oedema (DMO) subtypes using swept-source optical coherence tomography angiography (SS-OCTA).
methodsThis cross-sectional study analysed 182 eyes with centre-involved DMO from 141 patients (45 diffuse retinal thickening [DRT], 72 cystoid macular oedema [CMO], 65 serous retinal detachment [SRD]) and 40 age-matched healthy controls. Imaging was performed using the VG200 SS-OCTA system with a 1050 nm wavelength and 200,000 A-scans/second scan speed. Parameters including choroidal thickness (ChT), choroidal volume (CV), choroidal vascularity index (CVI), and choriocapillaris flow deficit percentage (CC FD%) were assessed in three macular annular regions (1-, 3-, and 6-mm diameter rings cantered on the fovea).
resultsCompared to controls, all DMO subtypes exhibited choroidal microvascular dysfunction, including reduced CVI and increased ChT. Notably, SRD demonstrated the most severe flow deficits, with significantly larger CC FD% than both DRT (17.08 ± 10.83% vs 11.08 ± 7.38%, p = 0.002) and CMO (17.08 ± 10.83% vs 12.71 ± 8.16%, p = 0.014) in the 1-mm diameter ring. Similar differences were observed in the 3-mm diameter ring (SRD 12.66 ± 5.73% vs DRT 9.09 ± 5.00%, p = 0.002; SRD vs CMO 9.84 ± 5.11%, p = 0.007) and 6-mm diameter ring (SRD 9.87 ± 4.03% vs DRT 8.11 ± 4.40%, p = 0.003; SRD vs CMO 8.28 ± 4.07%, p = 0.026). No significant inter-subtype differences were found in CVI or ChT (p > 0.05).
conclusionsChoroidal microvascular dysfunction is present in all DMO subtypes, with SRD exhibiting the most severe choriocapillaris flow deficits. These findings suggest potential subtype-specific pathophysiological associations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.