Evidence map›Paper›PMID 42151382›Full record

ArticleNature metabolism2026

Cardiolipin preserves T

Annamaria Regina, Francesca Solagna, Malkon Sanchez Estrada, Maaike M E Jacobs, Daniel Martinez-Martinez, Theodoros Georgomanolis, Irma Alibashikj, Sara Gjurgji, Claire Pearson, Dehui Chang and 22 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Annamaria ReginaInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0003-2041-2320
Francesca SolagnaInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0001-6607-2291
Malkon Sanchez EstradaInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Maaike M E JacobsMax Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Daniel Martinez-MartinezInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Theodoros GeorgomanolisCologne Excellence Cluster on Aging and Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0002-4066-9257
Irma AlibashikjInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Sara GjurgjiInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Claire PearsonKennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK.
Dehui ChangKennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-0864-9141
Chrysanthi MoschandreaCologne Excellence Cluster on Aging and Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Ana Sagrera AparisiCentro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, and Institute for Molecular Biology-IUBM, Universidad Autónoma de Madrid, Madrid, Spain.
Elena CrespoRoger Williams Institute of Liver Studies, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London University, and King's College Hospital, London, UK.
Jessica BuechelInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Farina SchneiderCologne Excellence Cluster on Aging and Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Lea TrojahnCologne Excellence Cluster on Aging and Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID http://orcid.org/0009-0004-9873-9256
Paulina PfelzerInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Milica PopovicCologne Excellence Cluster on Aging and Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0002-8762-6967
Elena PotenzaInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Agnieszka M KabatMax Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Carien NiessenCologne Excellence Cluster on Aging and Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0002-4892-9391
Borko AmulicUniversity of Bristol, Bristol, UK.
Niloufar SafiniaRoger Williams Institute of Liver Studies, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London University, and King's College Hospital, London, UK.
Sara CogliatiCentro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, and Institute for Molecular Biology-IUBM, Universidad Autónoma de Madrid, Madrid, Spain.ORCID http://orcid.org/0000-0002-0374-3489
David E SaninDepartment of Oncology, Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0003-0188-7267
Matteo VillaMax Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.ORCID http://orcid.org/0000-0003-2684-0596
Edward J PearceMax Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.
Christian FrezzaInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0002-3293-7397
Erika L PearceMax Planck Institute for Immunobiology and Epigenetics, Freiburg im Breisgau, Germany.ORCID http://orcid.org/0000-0001-5592-5439
Filipe CabreiroInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany.
Fiona PowrieKennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, UK.
Mauro CorradoInstitute for Genetics, Faculty of Mathematics and Natural Sciences, University of Cologne, Cologne, Germany. mcorrado@uni-koeln.de.ORCID http://orcid.org/0000-0002-0617-3274

Funding

Deutsche Forschungsgemeinschaft (German Research Foundation) 269925409-B12
6 · The paper itself

Abstract

Loss of host-microbiota balance promotes gut inflammation, colitis and inflammatory bowel disease. Yet, whether host or microbial factors are the critical driver of the pathology remains unclear. Here, we investigate how cardiolipin maintains metabolic fitness of regulatory T (T

Indexed as

CardiolipinsHomeostasisT-Lymphocytes, RegulatoryAnimalsBarth SyndromeColitisMiceCardiolipins

Identifiers

PMID42151382
PMCPMC13303090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.