Evidence map›Paper›PMID 42150340›Full record

ArticleInternational dental journal2026

Titanium Dioxide Particle Size Influences Macrophage Signal Switch Towards Osteogenesis In Vitro.

K G Aghila Rani, Zuha Rizvi, Savitha Suresh, A R Samsudin, Sausan AlKawas, Waad Kheder

Abstract read
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In one paragraph

Article in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

K G Aghila RaniResearch Institute for Medical and Health Sciences RIMHS, University of Sharjah, Sharjah, United Arab Emirates.
Zuha RizviResearch Institute for Medical and Health Sciences RIMHS, University of Sharjah, Sharjah, United Arab Emirates.
Savitha SureshResearch Institute for Medical and Health Sciences RIMHS, University of Sharjah, Sharjah, United Arab Emirates.
A R SamsudinDepartment of Oral & Craniofacial Health Sciences, College of Dental Medicine, University, of Sharjah, Sharjah, United Arab Emirates.
Sausan AlKawasDepartment of Oral & Craniofacial Health Sciences, College of Dental Medicine, University, of Sharjah, Sharjah, United Arab Emirates.
Waad KhederDepartment of Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah, United Arab Emirates. Electronic address: wkheder@sharjah.ac.ae.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the impact of titanium dioxide microparticles (TiO

designThe viability of THP-1-derived macrophages exposed to TiO

resultsBoth TiO

conclusionTitanium dioxide particle sizes are able to "switch" macrophage signalling toward either bone formation (nano) or bone resorption (micro) and may play a crucial role in osteo-immunomodulation.

Indexed as

MacrophagesOsteogenesisTitaniumBlotting, WesternCell SurvivalHumansNanoparticlesOsteoblastsOsteoprotegerinParticle SizeRANK LigandSignal TransductionOsteoprotegerinRANK LigandTitaniumtitanium dioxideMacrophagesMicroparticlesNanoparticlesOsteoblastsOsteogenesisTitanium dioxide

Identifiers

PMID42150340
PMCPMC13213282

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.