Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Jacqueline Condrau *Institute of Pharmacology and Toxicology, University of Zurich, Zurich 8057, Switzerland.
Srinivasa R Allu *Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Tatiana V EsipovaDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Eva ErlebachInstitute of Pharmacology and Toxicology, University of Zurich, Zurich 8057, Switzerland.
Matthias T WyssInstitute of Pharmacology and Toxicology, University of Zurich, Zurich 8057, Switzerland.ORCID 0000-0002-2037-3424
Chaim GlückInstitute of Pharmacology and Toxicology, University of Zurich, Zurich 8057, Switzerland.ORCID 0000-0002-8754-9965
Luca RavottoInstitute of Pharmacology and Toxicology, University of Zurich, Zurich 8057, Switzerland.ORCID 0000-0002-0431-9866
Thomas TroxlerDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Mikhail DrobizhevDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717.ORCID 0000-0001-9072-1300
Marco VillaG. Ciamician Department of Chemistry, University of Bologna, Bologna 40126, Italy.
Paola CeroniG. Ciamician Department of Chemistry, University of Bologna, Bologna 40126, Italy.
Mohamad El AmkiNeuroscience Center Zurich, University and ETH Zurich, Zurich 8057, Switzerland.ORCID 0000-0003-1245-5283
Sergei A VinogradovDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Bruno WeberInstitute of Pharmacology and Toxicology, University of Zurich, Zurich 8057, Switzerland.ORCID 0000-0002-9089-0689
Funding
Cherenkov Excited Luminescence Metabolic Sensing (CELMS)R01EB033877 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI Brian William Pogue, Sergei Vinogradov · 2024 to 2026
$1.7M
HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) EB028941HHS | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) EB033877HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS109107NIBIB NIH HHS R01 EB033877Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 310030_182703Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 310030_219656
6 · The paper itself
Abstract
The ability to induce endothelial cell (EC) damage in the mouse brain with high spatial precision is invaluable for mechanistic studies of brain capillary injury and repair. Here, we introduce an optical method, termed Endothelial Cell guided obliteration (ECgo), that utilizes a two-photon-excitable porphyrin-based photosensitizer (
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
ECgo: All-optical induction of single endothelial cell injury and capillary occlusion in the brain. · full record | OpenQuestion