ArticlePloS one2026
Maintaining function and participation through tailored 24-hour movement behaviours for people living with multiple long-term conditions and frailty (The PERSONAL-AGILITY study): Protocol for a randomised controlled feasibility trial.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMaintaining function and participation through tailored 24-hour movement behaviours for people living with multiple long-term conditions (MLTC) and frailty (The PERSONAL-AGILITY study) is a research programme which aims to develop and evaluate a complex behaviour change intervention. The intervention uses a range of approaches tailored for individuals living with MLTC and frailty, and their carers, incorporating novel technology to improve 24-hour movement behaviours and, consequently, quality of life and physical function. This paper outlines the protocol for a randomised controlled trial (RCT) evaluating the feasibility and acceptability of the PERSONAL-AGILITY intervention, study design and procedures. METHODS AND ANALYSIS: A feasibility RCT, with 2:1 allocation to the PERSONAL-AGILITY intervention or usual care control. The primary outcome is the feasibility and acceptability of a future definitive RCT investigating the effectiveness of the PERSONAL-AGILITY intervention, assessed against prespecified progression criteria, including eligibility, recruitment, retention, and outcome measure completion rates. The trial will be conducted at the University Hospitals of Leicester and comprise a 24-week tailored behaviour change intervention delivered by members of the PERSONAL-AGILITY research team. A target sample of 50 people with MLTC and frailty, and their carer (optional), will be recruited. A range of secondary outcomes including body composition, blood pressure, physical activity, sleep, physical function, and quality of life will be assessed at baseline, 12, and 24 weeks to help identify the primary or co-primary outcomes for participants with MLTC and frailty and their carers. A mixed methods process evaluation will examine the acceptability, feasibility and fidelity of intervention delivery and trial procedures. This study will inform the feasibility and design of a future definitive RCT. ETHICS AND DISSEMINATION: The trial has been approved by South Central Oxford B Research Ethics Committee (Ref: 24/SC/0367). Participants will be asked to provide consent to take part in the PERSONAL-AGILITY study by a trained member of the research team. Findings will be disseminated via peer reviewed journals, presentations and communications with health care professionals, patients and the public. Trial registration: International Standard Randomised Controlled Trial Number 14362764. URL to registry record: https://www.isrctn.com/ISRCTN14362764. Date of registration: 25th November 2024.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.