ArticleMethods in molecular biology (Clifton, N.J.)2026
The Evaluation of Fibrotic Alterations in Regenerated Murine and Human Xenografted Skin.
Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
6 authors.
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Abstract
This protocol delineates a methodological framework for the quantitative analysis of collagen architecture during the processes of skin regeneration and fibrosis. The protocol integrates skin regeneration modeling with advanced computational tools. The splinted wound model facilitates the observation of wound regeneration in mice and the evaluation of therapeutic interventions. The xenografting of human skin allows in vivo investigations of human skin regeneration and the monitoring of dynamic changes following therapy application. To objectively quantify these changes, we employ curvelet transform-based algorithms (CurveAlign and CT-FIRE), which allow clear fiber visualization at brightfield and fluorescent images and extraction of individual fiber parameters. We suggest an algorithm for standardizing data collection and analysis using open-access software for collagen fiber structure examination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.