Evidence map›Paper›PMID 42149398›Full record

ArticleIndian pediatrics2026

Subclinical Origins of Cardiometabolic Risk in Indian Adolescents: A Cross-Sectional Study.

Shalini G Hegde, Shreyas R Kankara, John Michael Raj, Babu Philip, Pratibha Dwarkanath, Anura V Kurpad

Abstract read
PubMed Publisher
In one paragraph

Article in Indian pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shalini G HegdeDepartment of Pediatric Surgery, St. John's Medical College, Sarjapur Road, Bengaluru, Karnataka, India.
Shreyas R KankaraDepartment of Radiology, St. John's Medical College, Sarjapur Road, Bengaluru, Karnataka, India.
John Michael RajDepartment of Biostatistics, St. John's Medical College, Sarjapur Road, Bengaluru, Karnataka, India.
Babu PhilipDepartment of Radiology, St. John's Medical College, Sarjapur Road, Bengaluru, Karnataka, India.
Pratibha DwarkanathDivision of Nutrition, St. John's Research Institute, Sarjapur Road, Bengaluru, Karnataka, India.
Anura V KurpadDepartment of Physiology, St. John's Medical College, Sarjapur Road, Bengaluru, Karnataka, 560034, India. a.kurpad@sjri.res.in.ORCID http://orcid.org/0000-0001-7998-2438

Funding

Intramural RS/2056/2024
6 · The paper itself

Abstract

objectiveTo measure and study the associations between body and hepatic fat and cardiometabolic risk (CMR) factors, in apparently healthy Indian adolescents.

methodsIn this cross-sectional study, anthropometry and CMR factors (glycosylated hemoglobin, lipid profile, seated blood pressure measurement) were measured in apparently healthy Indian adolescents aged 11-16 years. Hepatic fat was measured by MRI proton density fat fraction (PDFF) using a 3.0 T system (GE Signa Architect). Whole-body fat was measured by dual-energy X-ray absorptiometry (DXA).

resultsForty adolescents (24 boys) with a mean (SD) age of 14.3 (1.5) years were enrolled. At least one CMR factor was seen in 32.5% of all adolescents and in 18% of those who were normal body mass index (BMI). The prevalence of fatty liver was 5%. The waist circumference was significantly different between adolescents with CMR factors and those without (P = 0.003). Fat mass index (OR 2.08, 95% CI 1.17-3.68), total fat mass (OR 1.32, 95% CI 1.06-1.64), and truncal fat mass (OR 1.75, 95% CI 1.12-2.72) were positively associated with CMR and progression of hepatic steatosis. Fat in the android region had the maximum association with CMR (OR 30.54, 95% CI 2.09-445.98).

conclusionsCMR and hepatic steatosis are prevalent in Indian adolescents and can occur even at normal BMI, with android fat distribution being the strongest determinant of CMR. TRIAL REGISTRY: Clinical Trials Registry of India; Ref. No. CTRI/2024/06/068925.

Indexed as

Cardiometabolic Risk FactorsCardiovascular DiseasesAbsorptiometry, PhotonAdolescentBody Mass IndexChildCross-Sectional StudiesFatty LiverFemaleHumansIndiaMagnetic Resonance ImagingMaleRisk FactorsBody fatCentral adiposityDual X-ray absorptiometryFatty liverMRI PDFF

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.